Fangjun Jia
Overview
Explore the profile of Fangjun Jia including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
1387
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Recent Articles
1.
Huang M, Nguyen P, Jia F, Hu S, Gong Y, de Almeida P, et al.
Circulation
. 2011 Sep;
124(11 Suppl):S46-54.
PMID: 21911818
Background: Under normoxic conditions, hypoxia-inducible factor (HIF)-1α is rapidly degraded by 2 hydroxylases: prolyl hydroxylase (PHD) and factor-inhibiting HIF-1 (FIH). Because HIF-1α mediates the cardioprotective response to ischemic injury, its...
2.
Hu S, Huang M, Nguyen P, Gong Y, Li Z, Jia F, et al.
Circulation
. 2011 Sep;
124(11 Suppl):S27-34.
PMID: 21911815
Background: Although stem cell therapy has provided a promising treatment for myocardial infarction, the low survival of the transplanted cells in the infarcted myocardium is possibly a primary reason for...
3.
Narsinh K, Jia F, Robbins R, Kay M, Longaker M, Wu J
Nat Protoc
. 2011 Jan;
6(1):78-88.
PMID: 21212777
Human induced pluripotent stem cells (hiPSCs) derived from patient samples have tremendous potential for innovative approaches to disease pathology investigation and regenerative medicine therapies. However, most hiPSC derivation techniques use...
4.
Hu S, Huang M, Li Z, Jia F, Ghosh Z, Lijkwan M, et al.
Circulation
. 2010 Sep;
122(11 Suppl):S124-31.
PMID: 20837903
Background: MicroRNAs are involved in various critical functions, including the regulation of cellular differentiation, proliferation, angiogenesis, and apoptosis. We hypothesize that microRNA-210 can rescue cardiac function after myocardial infarction by...
5.
Wilson K, Hu S, Venkatasubrahmanyam S, Fu J, Sun N, Abilez O, et al.
Circ Cardiovasc Genet
. 2010 Aug;
3(5):426-35.
PMID: 20733065
Background: MicroRNAs (miRNAs) are a newly discovered endogenous class of small, noncoding RNAs that play important posttranscriptional regulatory roles by targeting messenger RNAs for cleavage or translational repression. Human embryonic...
6.
Jia F, Wilson K, Sun N, Gupta D, Huang M, Li Z, et al.
Nat Methods
. 2010 Feb;
7(3):197-9.
PMID: 20139967
Owing to the risk of insertional mutagenesis, viral transduction has been increasingly replaced by nonviral methods to generate induced pluripotent stem cells (iPSCs). We report the use of 'minicircle' DNA,...
7.
Li Z, Wilson K, Smith B, Kraft D, Jia F, Huang M, et al.
PLoS One
. 2010 Jan;
4(12):e8443.
PMID: 20046878
Background: Differentiation of human embryonic stem cells into endothelial cells (hESC-ECs) has the potential to provide an unlimited source of cells for novel transplantation therapies of ischemic diseases by supporting...
8.
Sun N, Panetta N, Gupta D, Wilson K, Lee A, Jia F, et al.
Proc Natl Acad Sci U S A
. 2009 Oct;
106(37):15720-5.
PMID: 19805220
Ectopic expression of transcription factors can reprogram somatic cells to a pluripotent state. However, most of the studies used skin fibroblasts as the starting population for reprogramming, which usually take...
9.
Huang M, Chen Z, Hu S, Jia F, Li Z, Hoyt G, et al.
Circulation
. 2009 Sep;
120(11 Suppl):S230-7.
PMID: 19752373
Background: Conventional plasmids for gene therapy produce low-level and short-term gene expression. In this study, we develop a novel nonviral vector that robustly and persistently expresses the hypoxia-inducible factor-1 alpha...
10.
Wilson K, Venkatasubrahmanyam S, Jia F, Sun N, Butte A, Wu J
Stem Cells Dev
. 2009 Mar;
18(5):749-58.
PMID: 19284351
MicroRNAs (miRNAs) are a newly discovered endogenous class of small noncoding RNAs that play important posttranscriptional regulatory roles by targeting mRNAs for cleavage or translational repression. Accumulating evidence now supports...