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Fabrizio Manetti

Explore the profile of Fabrizio Manetti including associated specialties, affiliations and a list of published articles. Areas
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Articles 159
Citations 1494
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Recent Articles
1.
Poggialini F, Governa P, Vagaggini C, Maramai S, Lamponi S, Mugnaini C, et al.
Eur J Pharm Sci . 2025 Mar; :107066. PMID: 40064401
The possibility to control the effects of drugs in time and space represents an ideal condition for developing safer and more personalized therapies against different disorders. In this context, photopharmacology...
2.
Di Maria S, Passannanti R, Poggialini F, Vagaggini C, Serafinelli A, Bianchi E, et al.
Eur J Med Chem . 2025 Jan; 286:117285. PMID: 39884903
No abstract available.
3.
Di Maria S, Passannanti R, Poggialini F, Vagaggini C, Serafinelli A, Bianchi E, et al.
Eur J Med Chem . 2024 Oct; 280:116929. PMID: 39406114
Hepatocellular carcinoma (HCC) is the most common type of liver solid tumor and the second leading cause of cancer-related deaths worldwide. Although new treatment options have been recently approved, the...
4.
Zhao F, Mattana A, Alam R, Montgomery S, Pandya A, Manetti F, et al.
Nat Commun . 2024 Sep; 15(1):8332. PMID: 39333478
Biocatalysis has been widely employed for the generation of carbon-carbon/heteroatom stereocentres, yet its application in chiral C(sp)-S bond construction is rare and limited to enzymatic kinetic resolutions. Herein, we describe...
5.
Aslan H, Renzi G, Angeli A, DAgostino I, Ronca R, Massardi M, et al.
RSC Med Chem . 2024 Jun; 15(6):1929-1941. PMID: 38911163
In the last decades, carbonic anhydrases (CAs) have become the top investigated innovative pharmacological targets and, in particular, isoforms IX and XII have been widely studied due to the evidence...
6.
Gori Savellini G, Anichini G, Manetti F, Trivisani C, Cusi M
Viruses . 2024 May; 16(5). PMID: 38793572
Non-structural protein 1 (Nsp1) represents one of the most crucial SARS-CoV-2 virulence factors by inhibiting the translation of host mRNAs and promoting their degradation. We selected naturally occurring virus lineages...
7.
Governa P, Biagi M, Manetti F, Forli S
RSC Med Chem . 2024 Feb; 15(2):720-732. PMID: 38389870
ATP-binding cassette (ABC) transporters are a large family of proteins involved in membrane transport of a wide variety of substrates. Among them, ABCB1, also known as MDR-1 or P-glycoprotein (P-gp),...
8.
Vagaggini C, Petroni D, DAgostino I, Poggialini F, Cavallini C, Cianciusi A, et al.
Drug Dev Res . 2024 Feb; 85(1):e22158. PMID: 38349262
Glioblastoma multiforme (GBM) is one of the most aggressive malignancies with a high recurrence rate and poor prognosis. Theranostic, combining therapeutic and diagnostic approaches, arises as a successful strategy to...
9.
Degiacomi G, Gianibbi B, Recchia D, Stelitano G, Truglio G, Marra P, et al.
ACS Omega . 2023 Jul; 8(28):25209-25220. PMID: 37483251
Treatment against tuberculosis can lead to the selection of drug-resistant strains. To tackle this serious threat, new targets from are needed to develop novel effective drugs. In this work, we...
10.
Maresca L, Crivaro E, Migliorini F, Anichini G, Giammona A, Pepe S, et al.
Pharmacol Res . 2023 Jul; 195:106858. PMID: 37473878
Aberrant activation of Hedgehog (HH) signaling in cancer is the result of genetic alterations of upstream pathway components (canonical) or other oncogenic mechanisms (noncanonical), that ultimately concur to activate the...