Fabien Alpy
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Explore the profile of Fabien Alpy including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
1133
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Recent Articles
11.
Tan B, Jaulin A, Bund C, Outilaft H, Wendling C, Chenard M, et al.
Cancers (Basel)
. 2020 Aug;
12(9).
PMID: 32825455
Matrix metalloproteinase 11 (MMP11) is an extracellular proteolytic enzyme belonging to the matrix metalloproteinase (MMP11) family. These proteases are involved in extracellular matrix (ECM) remodeling and activation of latent factors....
12.
Carrat G, Haythorne E, Tomas A, Haataja L, Muller A, Arvan P, et al.
Mol Metab
. 2020 May;
40:101015.
PMID: 32416313
Objective: Risk alleles for type 2 diabetes at the STARD10 locus are associated with lowered STARD10 expression in the β-cell, impaired glucose-induced insulin secretion, and decreased circulating proinsulin:insulin ratios. Although...
13.
Voilquin L, Di Mattia T, Alpy F
EMBO Rep
. 2020 Jan;
21(2):e49876.
PMID: 31919962
Enteroviruses, members of the Picornaviridae family, are non-enveloped and single-stranded RNA viruses responsible for several human diseases. During infection, these viruses build membrane-bound organelles, called replication organelles (ROs), where new...
14.
Di Mattia T, Tomasetto C, Alpy F
Biochim Biophys Acta Mol Cell Biol Lipids
. 2019 Jun;
1865(1):158490.
PMID: 31252175
Eukaryotic cells are partitioned into functionally distinct organelles. Long considered as independent units in the cytosol, organelles are actually in constant and direct interaction with each other, mostly through the...
15.
Reix N, Lodi M, Jankowski S, Moliere S, Luporsi E, Leblanc S, et al.
Clin Chem Lab Med
. 2019 Mar;
57(6):901-910.
PMID: 30838840
Background uPA and PAI-1 are breast cancer biomarkers that evaluate the benefit of chemotherapy (CT) for HER2-negative, estrogen receptor-positive, low or intermediate grade patients. Our objectives were to observe clinical...
16.
Wilhelm L, Voilquin L, Kobayashi T, Tomasetto C, Alpy F
Methods Mol Biol
. 2019 Feb;
1949:137-152.
PMID: 30790254
Cholesterol, a major component of biological membranes, is rapidly trafficked and unevenly distributed between organelles. Anomalies of intracellular cholesterol distribution are the hallmark of a number of lysosomal lipid storage...
17.
Di Mattia T, Tomasetto C, Alpy F
Med Sci (Paris)
. 2019 Jan;
35(1):23-25.
PMID: 30672451
No abstract available.
18.
Di Mattia T, Wilhelm L, Ikhlef S, Wendling C, Spehner D, Nomine Y, et al.
EMBO Rep
. 2018 Jun;
19(7).
PMID: 29858488
Membrane contact sites are cellular structures that mediate interorganelle exchange and communication. The two major tether proteins of the endoplasmic reticulum (ER), VAP-A and VAP-B, interact with proteins from other...
19.
Wilhelm L, Wendling C, Vedie B, Kobayashi T, Chenard M, Tomasetto C, et al.
EMBO J
. 2017 Apr;
36(10):1412-1433.
PMID: 28377464
StAR-related lipid transfer domain-3 (STARD3) is a sterol-binding protein that creates endoplasmic reticulum (ER)-endosome contact sites. How this protein, at the crossroad between sterol uptake and synthesis pathways, impacts the...
20.
De Arcangelis A, Hamade H, Alpy F, Normand S, Bruyere E, Lefebvre O, et al.
Gut
. 2016 Jul;
66(10):1748-1760.
PMID: 27371534
Objective: Epidemiological and clinical data indicate that patients suffering from IBD with long-standing colitis display a higher risk to develop colorectal high-grade dysplasia. Whereas carcinoma invasion and metastasis rely on...