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Fabian Erdel

Explore the profile of Fabian Erdel including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 1335
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Recent Articles
1.
Muzzopappa F, Erdel F
Curr Opin Genet Dev . 2025 Jan; 91:102304. PMID: 39813812
Membraneless subcompartments organize various activities in the cell nucleus. Some of them are formed through phase separation that is driven by the polymeric and multivalent nature of biomolecules. Here, we...
2.
Arnould C, Rocher V, Saur F, Bader A, Muzzopappa F, Collins S, et al.
Nature . 2023 Nov; 624(7990):E1. PMID: 37974007
No abstract available.
3.
Arnould C, Rocher V, Saur F, Bader A, Muzzopappa F, Collins S, et al.
Nature . 2023 Oct; 623(7985):183-192. PMID: 37853125
The DNA damage response is essential to safeguard genome integrity. Although the contribution of chromatin in DNA repair has been investigated, the contribution of chromosome folding to these processes remains...
4.
Hertzog M, Erdel F
Cells . 2023 Aug; 12(15). PMID: 37566037
Chromatin regulatory processes physically take place in the environment of the cell nucleus, which is filled with the chromosomes and a plethora of smaller biomolecules. The nucleus contains macromolecular assemblies...
5.
Dolde U, Muzzopappa F, Delesalle C, Neveu J, Erdel F, Vert G
iScience . 2023 Jun; 26(6):106880. PMID: 37260753
The transcription factor LEAFY (LFY) plays crucial roles in flower development by activating floral homeotic genes. Activation of LFY targets requires the combined action of LFY and the E3 ubiquitin...
6.
Erdel F
Curr Opin Struct Biol . 2023 Apr; 80:102597. PMID: 37087823
Heterochromatin formation has been proposed to involve phase transitions on the level of the three-dimensional folding of heterochromatin regions and the liquid-liquid demixing of heterochromatin proteins. Here, I outline the...
7.
Muckenhuber M, Seufert I, Muller-Ott K, Mallm J, Klett L, Knotz C, et al.
Life Sci Alliance . 2023 Feb; 6(4). PMID: 36732019
The antiviral response induced by type I interferon (IFN) via the JAK-STAT signaling cascade activates hundreds of IFN-stimulated genes (ISGs) across human and mouse tissues but varies between cell types....
8.
Muzzopappa F, Hummert J, Anfossi M, Tashev S, Herten D, Erdel F
Nat Commun . 2022 Dec; 13(1):7787. PMID: 36526633
Cells contain numerous substructures that have been proposed to form via liquid-liquid phase separation (LLPS). It is currently debated how to reliably distinguish LLPS from other mechanisms. Here, we benchmark...
9.
Rademacher A, Erdel F, Weinmann R, Rippe K
Methods Mol Biol . 2022 Oct; 2563:395-411. PMID: 36227485
Phase separation is emerging as a key mechanism to describe the formation of membraneless organelles in the cell. It depends on the multivalent (self-) interaction properties of the macromolecules involved...
10.
Frank L, Weinmann R, Erdel F, Trojanowski J, Rippe K
Methods Mol Biol . 2021 Aug; 2351:307-320. PMID: 34382197
The transition from silenced heterochromatin to a biologically active state and vice versa is a fundamental part of the implementation of cell type-specific gene expression programs. To reveal structure-function relationships...