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Jorge Trojanowski

Explore the profile of Jorge Trojanowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 97
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Recent Articles
1.
Trojanowski J, Frank L, Rademacher A, Mucke N, Grigaitis P, Rippe K
Mol Cell . 2022 May; 82(10):1878-1893.e10. PMID: 35537448
Transcription factors (TFs) consist of a DNA-binding domain and an activation domain (AD) that are frequently considered to be independent and exchangeable modules. However, recent studies report that the physicochemical...
2.
Frank L, Weinmann R, Erdel F, Trojanowski J, Rippe K
Methods Mol Biol . 2021 Aug; 2351:307-320. PMID: 34382197
The transition from silenced heterochromatin to a biologically active state and vice versa is a fundamental part of the implementation of cell type-specific gene expression programs. To reveal structure-function relationships...
3.
Rademacher A, Erdel F, Trojanowski J, Rippe K
Methods Mol Biol . 2020 Jul; 2173:171-188. PMID: 32651918
Blue light-induced chromatin recruitment (BLInCR) is a versatile optogenetic tool to enrich effector proteins at specific loci within the nucleus using illumination in the 400-500 nm range. The resulting chromatin...
4.
Trojanowski J, Rademacher A, Erdel F, Rippe K
Methods Mol Biol . 2019 Aug; 2038:251-270. PMID: 31407290
Gene expression can be monitored in living cells via the binding of fluorescently tagged proteins to RNA repeats engineered into a reporter transcript. This approach makes it possible to trace...
5.
Rademacher A, Erdel F, Trojanowski J, Schumacher S, Rippe K
J Cell Sci . 2017 Nov; 130(24):4213-4224. PMID: 29122982
Gene expression is tightly regulated in space and time. To dissect this process with high temporal resolution, we introduce an optogenetic tool termed blue light-induced chromatin recruitment (BLInCR) that combines...