F W Flitney
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Explore the profile of F W Flitney including associated specialties, affiliations and a list of published articles.
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45
Citations
511
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Recent Articles
1.
Yoon K, Yoon M, Moir R, Khuon S, Flitney F, Goldman R
J Cell Biol
. 2001 May;
153(3):503-16.
PMID: 11331302
The properties of keratin intermediate filaments (IFs) have been studied after transfection with green fluorescent protein (GFP)-tagged K18 and/or K8 (type I/II IF proteins). GFP-K8 and -K18 become incorporated into...
2.
Gonzales M, Weksler B, Tsuruta D, Goldman R, Yoon K, Hopkinson S, et al.
Mol Biol Cell
. 2001 Feb;
12(1):85-100.
PMID: 11160825
The alpha4 laminin subunit is a component of endothelial cell basement membranes. An antibody (2A3) against the alpha4 laminin G domain stains focal contact-like structures in transformed and primary microvascular...
3.
Megson I, Holmes S, Magid K, PRITCHARD R, Flitney F
Br J Pharmacol
. 2000 Aug;
130(7):1575-80.
PMID: 10928960
Photorelaxation of vascular smooth muscle (VSM) is caused by the release of nitric oxide (NO) from a finite molecular store that can be depleted by irradiating pre-contracted arteries with visible...
4.
Butler A, Al-Sadoni H, Megson I, Flitney F
Nitric Oxide
. 1998 Sep;
2(3):193-202.
PMID: 9731637
A number of amino acid methyl esters have been coupled to N-acetylpenicillamine to give a range of sulfur-containing dipeptides. These have been nitrosated to give a family of structurally related...
5.
Fricker S, Slade E, POWELL N, Vaughan O, Henderson G, Murrer B, et al.
Br J Pharmacol
. 1998 Jan;
122(7):1441-9.
PMID: 9421293
1. Ruthenium(III) reacts with nitric oxide (NO) to form stable ruthenium(II) mononitrosyls. Several Ru(III) complexes were synthesized and a study made of their ability to bind NO, in vitro and...
6.
Al-Sadoni H, Megson I, Bisland S, Butler A, Flitney F
Br J Pharmacol
. 1997 Jul;
121(6):1047-50.
PMID: 9249237
1. A study has been made of the effect of neocuproine, a specific Cu(I) chelator, on vasodilator responses of rat isolated perfused tail artery to two nitrosothiols: S-nitroso-N-acetyl-D,L-penicillamine (SNAP) and...
7.
Butler A, Field R, Greig I, Flitney F, Bisland S, Khan F, et al.
Nitric Oxide
. 1997 Jun;
1(3):211-7.
PMID: 9704582
A number of S-nitrosated compounds derived from 1-thiosugars (glucose, galactose, xylose, maltose, and lactose) have been prepared and characterized. Most of the compounds obtained were unstable either as solids or...
8.
Burns D, Ruddock M, Brown J, Kennovin G, Dykes E, Flitney F, et al.
Biochem Soc Trans
. 1997 Feb;
25(1):132S.
PMID: 9057030
No abstract available.
9.
Flitney F, Megson I, Thomson J, Kennovin G, Butler A
Br J Pharmacol
. 1996 Apr;
117(7):1549-57.
PMID: 8730753
1. The vasodilator properties and photochemical decomposition of two synthetic iron-sulphur-nitrosyl clusters (cluster A: [Fe4S4(NO)4], tetranitrosyl-tetra-mu 3-sulphido-tetrahedro-tetrairon; and B:[Fe4S3 (NO)7]-1, heptanitrosyl-tri-mu 3-thioxotetraferrate(-1)) have been investigated. Experiments were carried out on...
10.
Askew S, Butler A, Flitney F, Kemp G, Megson I
Bioorg Med Chem
. 1995 Jan;
3(1):1-9.
PMID: 8612040
The chemistries of S-nitroso-DL-penicillamine (SNAP) and S-nitrosoglutathione (GSNO) in relation to their ability to relax vascular smooth muscle and prevent platelet aggregation have been investigated. Metal ion catalysis greatly accelerates...