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F Kojima

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Articles 79
Citations 504
Followers 0
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Recent Articles
1.
Ishida M, Kojima F, Okabe H
J Eur Acad Dermatol Venereol . 2012 Jan; 27(1):e128-30. PMID: 22220587
Background: Cathepsin K is a cysteine protease with strong collagenolytic and elastolytic properties. Recently, cathepsin K expression in tumour cells of malignant melanoma and in the stromal cells of squamous...
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Honda M, Hori Y, Shionoya Y, Yamamoto K, Kojima F, Nakamura T
Dis Esophagus . 2011 Sep; 25(3):269-72. PMID: 21883658
No conservative treatments for chylothorax have yet been established, and surgical ligation of the thoracic duct is required in many cases. In the present study, we investigated the management of...
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Monrad S, Kojima F, Kapoor M, Kuan E, Sarkar S, Randolph G, et al.
Prostaglandins Leukot Essent Fatty Acids . 2010 Dec; 84(3-4):113-21. PMID: 21190819
We undertook this study to determine the role of Microsomal PGE Synthase-1 (mPGES-1), and mPGES-1-generated Prostaglandin (PG) E2 on Dendritic Cell (DC) phenotype and function. Using mPGES-1 KnockOut (KO) mice,...
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Yuhki K, Kashiwagi H, Kojima F, Kawabe J, Ushikubi F
Int Angiol . 2010 Apr; 29(2 Suppl):19-27. PMID: 20357745
The roles of prostanoids in the pathogenesis of cardiovascular diseases and in the development of pathological conditions have been examined using mice lacking the individual, specific prostanoid receptor. Prostaglandin (PG)...
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Akiyama T, Abe M, Harada S, Kojima F, Sawa R, Takahashi Y, et al.
J Antibiot (Tokyo) . 2001 Nov; 54(9):744-6. PMID: 11714231
No abstract available.
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Rathbone M, Kinder J, Fike K, Kojima F, Clopton D, Ogle C, et al.
Adv Drug Deliv Rev . 2001 Aug; 50(3):277-320. PMID: 11500232
When methods of drug intervention are being developed to control estrous cycles, a thorough understanding of the endocrine and functional changes together with the reproductive behavior of the animals are...
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Kondo K, Adachi H, Shitara E, Kojima F, Nishimura Y
Bioorg Med Chem . 2001 May; 9(5):1091-5. PMID: 11377167
The relationships between structures and inhibitory activities of glycosidase inhibitors of gem-diamine 1-N-iminosugars in media of enzyme assays have been investigated. It has been proved that gem-diamine 1-N-iminosugar smoothly undergoes...
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Nishimura Y, Adachi H, Satoh T, Shitara E, Nakamura H, Kojima F, et al.
J Org Chem . 2000 Aug; 65(16):4871-82. PMID: 10956466
An efficient and general synthetic route to all eight stereoisomeric D-glycono-delta-lactams has been developed. The strategy involves, as a key step, a stereodivergent delta-lactam formation with configurational retention or inversion...
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Murakami M, Naraba H, Tanioka T, Semmyo N, Nakatani Y, Kojima F, et al.
J Biol Chem . 2000 Jun; 275(42):32783-92. PMID: 10869354
Here we report the molecular identification of membrane-bound glutathione (GSH)-dependent prostaglandin (PG) E(2) synthase (mPGES), a terminal enzyme of the cyclooxygenase (COX)-2-mediated PGE(2) biosynthetic pathway. The activity of mPGES was...