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Ezequiel Marron Fernandez de Velasco

Explore the profile of Ezequiel Marron Fernandez de Velasco including associated specialties, affiliations and a list of published articles. Areas
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Citations 594
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Recent Articles
1.
Moore M, Person K, Alwin A, Krusemark C, Foster N, Ray C, et al.
Res Sq . 2024 Dec; PMID: 39711540
G protein-coupled receptors (GPCRs), the largest family of drug targets, can signal through 16 subtypes of Gα proteins. Biased compounds that selectively activate therapy-relevant pathways promise to be safer, more...
2.
Moore M, Person K, Alwin A, Krusemark C, Foster N, Ray C, et al.
bioRxiv . 2024 Nov; PMID: 39605353
G protein-coupled receptors (GPCRs), the largest family of drug targets, can signal through 16 subtypes of Gα proteins. Biased compounds that selectively activate therapy-relevant pathways promise to be safer, more...
3.
Toddes C, Lefevre E, Retzlaff C, Zugschwert L, Khan S, Myhre E, et al.
bioRxiv . 2024 Nov; PMID: 39553981
Mu opioid receptors in the nucleus accumbens regulate motivated behavior, including pursuit of natural rewards like social interaction as well as exogenous opioids. We used a suite of genetic and...
4.
Luo H, Anderson A, Masuho I, Marron Fernandez de Velasco E, Birnbaumer L, Martemyanov K, et al.
Prog Neurobiol . 2024 Nov; 243:102686. PMID: 39542413
Most neurons are influenced by multiple neuromodulatory inputs that converge on common effectors. Mechanisms that route these signals are key to selective neuromodulation but are poorly understood. G protein-gated inwardly...
5.
Luo H, Frederick M, Marron Fernandez de Velasco E, Oltmanns J, Wright C, Wickman K
Learn Mem . 2024 Oct; 31(9). PMID: 39375002
G protein-gated inwardly rectifying K (GIRK) channels mediate the postsynaptic inhibitory effect of many neurotransmitters in the hippocampus and are implicated in neurological disorders characterized by cognitive deficits. Here, we...
6.
Mitten E, Souders A, Marron Fernandez de Velasco E, Aguado C, Lujan R, Wickman K
Br J Pharmacol . 2024 Oct; 182(1):69-86. PMID: 39358985
Background And Purpose: GABAergic neurons in mouse ventral tegmental area (VTA) exhibit elevated activity during withdrawal following chronic ethanol exposure. While increased glutamatergic input and decreased GABA receptor sensitivity have...
7.
Luo H, Marron Fernandez de Velasco E, Gansemer B, Frederick M, Aguado C, Lujan R, et al.
Sci Signal . 2024 Oct; 17(856):eado4132. PMID: 39353038
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by amyloid plaques and cognitive decline, the latter of which is thought to be driven by soluble oligomeric amyloid-β (oAβ). The...
8.
Weaver S, Torres H, Arnold K, Zars E, Peralta-Herrera E, Taylor E, et al.
JBMR Plus . 2024 Sep; 8(10):ziae108. PMID: 39228688
Osteoporosis and other metabolic bone diseases are prevalent in the aging population. While bone has the capacity to regenerate throughout life, bone formation rates decline with age and contribute to...
9.
Mitten E, Souders A, Marron Fernandez de Velasco E, Wickman K
Front Behav Neurosci . 2024 Aug; 18:1425607. PMID: 39086371
Introduction: Stress and trauma are significant risk factors for many neuropsychiatric disorders and diseases, including anxiety disorders. Stress-induced anxiety symptoms have been attributed to enhanced excitability in circuits controlling fear,...
10.
Gore R, Esmail T, Pflepsen K, Marron Fernandez de Velasco E, Kitto K, Riedl M, et al.
Front Pain Res (Lausanne) . 2023 Aug; 4:1225246. PMID: 37599864
Investigation of neural circuits underlying visceral pain is hampered by the difficulty in achieving selective manipulations of individual circuit components. In this study, we adapted a dual AAV approach, used...