Eva Geuens
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Explore the profile of Eva Geuens including associated specialties, affiliations and a list of published articles.
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11
Citations
190
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Recent Articles
1.
Van Acker Z, Luyckx E, Van Leuven W, Geuens E, De Deyn P, Van Dam D, et al.
FEBS Lett
. 2017 Apr;
591(10):1321-1332.
PMID: 28391636
Although neuroglobin confers neuroprotection against Alzheimer's disease (AD) pathology, its expression becomes downregulated in late-stage AD. Here, we provide evidence that indicates that this decrease is associated with the AD-linked...
2.
Kiger L, Tilleman L, Geuens E, Hoogewijs D, Lechauve C, Moens L, et al.
PLoS One
. 2011 Jun;
6(6):e20478.
PMID: 21674044
Caenorhabditis elegans globin GLB-26 (expressed from gene T22C1.2) has been studied in comparison with human neuroglobin (Ngb) and cytoglobin (Cygb) for its electron transfer properties. GLB-26 exhibits no reversible binding...
3.
Tilleman L, Germani F, De Henau S, Geuens E, Hoogewijs D, Braeckman B, et al.
IUBMB Life
. 2011 Mar;
63(3):166-74.
PMID: 21445847
Extensive in silico search of the genome of Caenorhabditis elegans revealed the presence of 33 genes coding for globins that are all transcribed. These globins are very diverse in gene...
4.
Geuens E, Hoogewijs D, Nardini M, Vinck E, Pesce A, Kiger L, et al.
BMC Biochem
. 2010 Apr;
11:17.
PMID: 20361867
Background: The genome of the nematode Caenorhabditis elegans contains more than 30 putative globin genes that all are transcribed. Although their translated amino acid sequences fit the globin fold, a...
5.
Hoogewijs D, Geuens E, Dewilde S, Vierstraete A, Moens L, Vinogradov S, et al.
BMC Genomics
. 2007 Oct;
8:356.
PMID: 17916248
Background: The emergence of high throughput genome sequencing facilities and powerful high performance bioinformatic tools has highlighted hitherto unexpected wide occurrence of globins in the three kingdoms of life. In...
6.
Deng P, Nienhaus K, Palladino P, Olson J, Blouin G, Moens L, et al.
Gene
. 2007 May;
398(1-2):208-23.
PMID: 17531406
The monomeric hemoglobin of the nemertean worm Cerebratulus lacteus functions as an oxygen storage protein to maintain neural activity under hypoxic conditions. It shares a large, apolar matrix tunnel with...
7.
Hundahl C, Kelsen J, Kjaer K, Biilmann Ronn L, Weber R, Geuens E, et al.
Brain Res
. 2006 May;
1085(1):19-27.
PMID: 16647691
Neuroglobin (NGB) is a recently characterized heme globin expressed primarily in retinal nerve cells and at very low levels in endocrine-active regions of vertebrate brains. When artificially over-expressed, NGB reduces...
8.
Hoogewijs D, Geuens E, Dewilde S, Moens L, Vierstraete A, Vinogradov S, et al.
IUBMB Life
. 2005 Apr;
56(11-12):697-702.
PMID: 15804834
The aim of our study was to annotate sequences for 35 putative globins from the nematode Caenorhabditis elegans. All these proteins are expressed, but seven of these differ from the...
9.
Pesce A, Nardini M, Ascenzi P, Geuens E, Dewilde S, Moens L, et al.
J Biol Chem
. 2004 May;
279(32):33662-72.
PMID: 15161908
The mini-hemoglobin from Cerebratulus lacteus (CerHb) belongs to a class of globins containing the polar Tyr-B10/Gln-E7 amino acid pair that normally causes low rates of O2 dissociation and ultra-high O2...
10.
Geuens E, Brouns I, Flamez D, Dewilde S, Timmermans J, Moens L
J Biol Chem
. 2003 Jun;
278(33):30417-20.
PMID: 12796507
Cytoglobin and neuroglobin are recently discovered members of the globin family. In situ hybridization localized neuroglobin mainly in brain and retina, while cytoglobin was expressed ubiquitously in all analyzed tissues....