Sylvia Dewilde
Overview
Explore the profile of Sylvia Dewilde including associated specialties, affiliations and a list of published articles.
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Articles
142
Citations
2737
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Recent Articles
1.
Pesce A, Barmpidi K, Dewilde S, Estarellas C, Moens L, Bolognesi M, et al.
J Inorg Biochem
. 2023 Jun;
246:112289.
PMID: 37354606
High energy consumption in the nervous system requires a continuous supply of O. This role is assisted by proteins from the globin super-family in the nerve cells of invertebrates, where...
2.
Van Brempt N, Sgammato R, Beirinckx Q, Hammerschmid D, Sobott F, Dewilde S, et al.
Biochim Biophys Acta Proteins Proteom
. 2023 Apr;
1871(4):140913.
PMID: 37004900
Out of the 34 globins in Caenorhabditis elegans, GLB-33 is a putative globin-coupled transmembrane receptor with a yet unknown function. The globin domain (GD) contains a particularly hydrophobic haem pocket,...
3.
Sgammato R, Van Brempt N, Aerts R, Van Doorslaer S, Dewilde S, Herrebout W, et al.
Dalton Trans
. 2023 Jan;
52(10):2976-2987.
PMID: 36651272
Protoglobin from (Pgb) is a dimeric globin belonging to the same lineage of the globin superfamily as globin-coupled sensors. A putative role in the scavenging of reactive nitrogen and oxygen...
4.
Hafideddine Z, Loier T, Van Brempt N, De Henau S, Ching H, Neukermans S, et al.
J Inorg Biochem
. 2022 Nov;
238:112063.
PMID: 36370505
The popular genetic model organism Caenorhabditis elegans (C. elegans) encodes 34 globins, whereby the few that are well-characterized show divergent properties besides the typical oxygen carrier function. Here, we present...
5.
Keppner A, Correia M, Santambrogio S, Koay T, Maric D, Osterhof C, et al.
Elife
. 2022 Jun;
11.
PMID: 35700329
Spermatogenesis is a highly specialized differentiation process driven by a dynamic gene expression program and ending with the production of mature spermatozoa. Whereas hundreds of genes are known to be...
6.
De Backer J, Maric D, Bosman M, Dewilde S, Hoogewijs D
Sci Rep
. 2021 May;
11(1):10879.
PMID: 34035373
Cytoglobin (CYGB) is a ubiquitously expressed protein with a protective role against oxidative stress, fibrosis and tumor growth, shown to be transcriptionally regulated under hypoxic conditions. Hypoxia-inducible CYGB expression is...
7.
Hammerschmid D, Germani F, Drusin S, Fagnen C, Schuster C, Hoogewijs D, et al.
Comput Struct Biotechnol J
. 2021 May;
19:1874-1888.
PMID: 33995893
Globin-coupled sensors (GCS) usually consist of three domains: a sensor/globin, a linker, and a transmitter domain. The globin domain (GD), activated by ligand binding and/or redox change, induces an intramolecular...
8.
Kumar N, Perez-Novo C, Shaw P, Logie E, Privat-Maldonado A, Dewilde S, et al.
Free Radic Biol Med
. 2021 Feb;
166:187-200.
PMID: 33636332
Despite modern therapeutic advances, the survival prospects of pancreatic cancer patients remain poor, due to chemoresistance and dysregulated oncogenic kinase signaling networks. We applied a novel kinome activity-mapping approach using...
9.
Attri P, Park J, De Backer J, Kim M, Yun J, Heo Y, et al.
Int J Biol Macromol
. 2020 Sep;
163:2405-2414.
PMID: 32961197
NADPH oxidases 1 (NOX1) derived reactive oxygen species (ROS) play an important role in the progression of cancer through signaling pathways. Therefore, in this paper, we demonstrate the effect of...
10.
Giordano D, Pesce A, Vermeylen S, Abbruzzetti S, Nardini M, Marchesani F, et al.
Comput Struct Biotechnol J
. 2020 Sep;
18:2132-2144.
PMID: 32913582
While the functions of the recently discovered cytoglobin, ubiquitously expressed in vertebrate tissues, remain uncertain, Antarctic fish provide unparalleled models to study novel protein traits that may arise from cold...