Erzsebet Paszti-Gere
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Explore the profile of Erzsebet Paszti-Gere including associated specialties, affiliations and a list of published articles.
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26
Citations
191
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Recent Articles
1.
Maluck S, Bobrovsky R, Poor M, Lange R, Steinmetzer T, Jerzsele A, et al.
Biomedicines
. 2024 Sep;
12(9).
PMID: 39335588
Inhibitors of the serine protease furin have been widely studied as antimicrobial agents due to their ability to block the cleavage and activation of certain viral surface proteins and bacterial...
2.
Gamba D, van Eijk N, Lanyi K, Monostory K, Steinmetzer T, Marosi A, et al.
Sci Rep
. 2024 Jul;
14(1):16621.
PMID: 39025978
Certain corona- and influenza viruses utilize type II transmembrane serine proteases for cell entry, making these enzymes potential drug targets for the treatment of viral respiratory infections. In this study,...
3.
van Niekerk A, Maluck S, Mag P, Kovago C, Kerek A, Jerzsele A, et al.
Biomedicines
. 2024 Apr;
12(4).
PMID: 38672139
The increasing prevalence of antimicrobial resistance against zoonotic bacteria, including , highlights the need for new therapeutical strategies, including the repositioning of drugs. In this study, susceptibilities of bacterial isolates...
4.
van Eijk N, Schmacke L, Steinmetzer T, Pilgram O, Poor M, Paszti-Gere E
Biomed Pharmacother
. 2023 Oct;
168:115761.
PMID: 37865989
The outbreak of coronavirus disease 2019 (COVID-19) pandemic strongly stimulated the development of small molecule antivirals selectively targeting type II transmembrane serine proteases (TTSP), required for the host-cell entry of...
5.
Silva C, Salmanzade K, Borbath I, Dodony E, Olasz D, Safran G, et al.
Nanomaterials (Basel)
. 2023 Aug;
13(15).
PMID: 37570561
The composites of transition metal-doped titania and carbon have emerged as promising supports for Pt electrocatalysts in PEM fuel cells. In these multifunctional supports, the oxide component stabilizes the Pt...
6.
Lanyi K, Monostory K, Steinmetzer T, Jerzsele A, Paszti-Gere E
Biomedicines
. 2023 Mar;
11(3).
PMID: 36979660
Type II transmembrane serine proteases represent pharmacological targets for blocking entry and spread of influenza or coronaviruses. In this study, the depletion rates of the 3-amidinophenylalanine (3-APhA)-derived matriptase/TMPRSS2 inhibitors MI-463,...
7.
Wohlert A, Palkovicsne Pezsa N, Moritz A, Jerzsele A, Farkas O, Paszti-Gere E
Animals (Basel)
. 2022 Oct;
12(20).
PMID: 36290134
Ochratoxin A (OTA) and lipopolysaccharide (LPS) intake can cause gastrointestinal disorders. Polyphenolic chrysin (CHR) and luteolin (LUT) display anti-inflammatory and antioxidant properties. Porcine intestinal epithelial (jejunal) IPEC-J2 cells were treated...
8.
Paszti-Gere E, Szentkiralyi-Toth A, Szabo P, Steinmetzer T, Fliszar-Nyul E, Poor M
Biomed Pharmacother
. 2022 May;
151:113124.
PMID: 35594709
The substrate-analog furin inhibitor MI-1851 can suppress the cleavage of SARS-CoV-2 spike protein and consequently produces significant antiviral effect on infected human airway epithelial cells. In this study, the interaction...
9.
Fedor Z, Szentkiralyi-Toth A, Nagy G, Szimrok Z, Varga E, Paszti A, et al.
Vet Sci
. 2022 Apr;
9(4).
PMID: 35448654
In vitro models of animals vulnerable to SARS-CoV-2 infection can support the characterization of effective antiviral drugs, such as synthetic inhibitors of the transmembrane protease serine 2 (TMPRSS2). Changes in...
10.
Paszti-Gere E, Szentkiralyi A, Fedor Z, Nagy G, Szimrok Z, Paszti Z, et al.
Biomed Pharmacother
. 2021 Dec;
146:112513.
PMID: 34915414
The interactions of four sulfonylated Phe(3-Am)-derived inhibitors (MI-432, MI-463, MI-482 and MI-1900) of type II transmembrane serine proteases (TTSP) such as transmembrane protease serine 2 (TMPRSS2) were examined with serum...