Erin E Stebbins
Overview
Explore the profile of Erin E Stebbins including associated specialties, affiliations and a list of published articles.
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9
Citations
180
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Recent Articles
1.
Hasan M, Mattice E, Teixeira J, Jumani R, Stebbins E, Klopfer C, et al.
PLoS Pathog
. 2024 Apr;
20(4):e1011906.
PMID: 38669269
The apicomplexan parasite Cryptosporidium is a leading cause of childhood diarrhea in developing countries. Current treatment options are inadequate and multiple preclinical compounds are being actively pursued as potential drugs...
2.
Schubert T, Oboh E, Peek H, Philo E, Teixeira J, Stebbins E, et al.
J Med Chem
. 2023 Jun;
66(12):7834-7848.
PMID: 37267631
Our previous work identified compound (SLU-2633) as a potent lead compound toward the identification of a novel treatment for cryptosporidiosis, caused by the parasite (EC = 0.17 μM). While this...
3.
Oboh E, Schubert T, Teixeira J, Stebbins E, Miller P, Philo E, et al.
J Med Chem
. 2021 Aug;
64(15):11729-11745.
PMID: 34342443
Cryptosporidiosis is caused by infection of the small intestine by parasites, resulting in severe diarrhea, dehydration, malabsorption, and potentially death. The only FDA-approved therapeutic is only partially effective in young...
4.
Hasan M, Stebbins E, Choy R, Gillespie J, de Hostos E, Miller P, et al.
Antimicrob Agents Chemother
. 2021 Mar;
65(6).
PMID: 33753338
The intestinal protozoan is a leading cause of diarrheal disease and mortality in young children. There is currently no fully effective treatment for cryptosporidiosis, which has stimulated interest in anticryptosporidial...
5.
Vinayak S, Jumani R, Miller P, Hasan M, McLeod B, Tandel J, et al.
Sci Transl Med
. 2020 Oct;
12(563).
PMID: 32998973
is a protozoan parasite and a leading cause of diarrheal disease and mortality in young children. Currently, there are no fully effective treatments available to cure infection with this diarrheal...
6.
Ehrenkaufer G, Li P, Stebbins E, Kangussu-Marcolino M, Debnath A, White C, et al.
PLoS Negl Trop Dis
. 2020 Mar;
14(3):e0008150.
PMID: 32196500
Parasitic infections are a major source of human suffering, mortality, and economic loss, but drug development for these diseases has been stymied by the significant expense involved in bringing a...
7.
Lunde C, Stebbins E, Jumani R, Hasan M, Miller P, Barlow J, et al.
Nat Commun
. 2019 Jun;
10(1):2816.
PMID: 31249291
Cryptosporidiosis is a leading cause of life-threatening diarrhea in young children and causes chronic diarrhea in AIDS patients, but the only approved treatment is ineffective in malnourished children and immunocompromised...
8.
Jumani R, Hasan M, Stebbins E, Donnelly L, Miller P, Klopfer C, et al.
Nat Commun
. 2019 Apr;
10(1):1862.
PMID: 31015448
Cryptosporidiosis is a leading cause of life-threatening diarrhea in children, and the only currently approved drug is ineffective in malnourished children and immunocompromised people. Large-scale phenotypic screens are ongoing to...
9.
Baragana B, Forte B, Choi R, Hewitt S, Bueren-Calabuig J, Pisco J, et al.
Proc Natl Acad Sci U S A
. 2019 Mar;
116(14):7015-7020.
PMID: 30894487
Malaria and cryptosporidiosis, caused by apicomplexan parasites, remain major drivers of global child mortality. New drugs for the treatment of malaria and cryptosporidiosis, in particular, are of high priority; however,...