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Erik P Lillehoj

Explore the profile of Erik P Lillehoj including associated specialties, affiliations and a list of published articles. Areas
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Articles 114
Citations 2422
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Recent Articles
1.
Lillehoj E, Yu Y, Verceles A, Imamura A, Ishida H, Piepenbrink K, et al.
iScience . 2024 Sep; 27(9):110866. PMID: 39314239
(Sm), a multidrug-resistant pathogen often isolated from immunocompromised individuals, presents its flagellin to multimeric tandem repeats within the ectodomain of mucin-1 (MUC1-ED), expressed on airway epithelia. Flagellated Sm increases neuraminidase-1...
2.
Hyun S, Feng C, Liu A, Lillehoj E, Trotta R, Kingsbury T, et al.
Sci Rep . 2022 Aug; 12(1):14173. PMID: 35986080
To gain insight into sialic acid biology and sialidase/neuraminidase (NEU) expression in mature human neutrophil (PMN)s, we studied NEU activity and expression in PMNs and the HL60 promyelocytic leukemic cell...
3.
Lillehoj E, Luzina I, Atamas S
Front Immunol . 2022 Apr; 13:883079. PMID: 35479093
Mammalian neuraminidases (NEUs), also known as sialidases, are enzymes that cleave off the terminal neuraminic, or sialic, acid resides from the carbohydrate moieties of glycolipids and glycoproteins. A rapidly growing...
4.
Verceles A, Bhat P, Nagaria Z, Martin D, Patel H, Ntem-Mensah A, et al.
Sci Rep . 2021 Nov; 11(1):22725. PMID: 34811449
We previously reported that flagellin-expressing Pseudomonas aeruginosa (Pa) provokes NEU1 sialidase-mediated MUC1 ectodomain (MUC1-ED) desialylation and MUC1-ED shedding from murine lungs in vivo. Here, we asked whether Pa in the...
5.
Hyun S, Imamura A, Ishida H, Piepenbrink K, Goldblum S, Lillehoj E
J Biol Chem . 2021 Oct; 297(5):101337. PMID: 34688655
The extracellular domain (ED) of the membrane-spanning sialoglycoprotein, mucin-1 (MUC1), is an in vivo substrate for the lysosomal sialidase, neuraminidase-1 (NEU1). Engagement of the MUC1-ED by its cognate ligand, Pseudomonas...
6.
Gadde U, Oh S, Lillehoj H, Lillehoj E
Sci Rep . 2021 Jan; 11(1):2892. PMID: 33510325
No abstract available.
7.
Luzina I, Lillehoj E, Lockatell V, Hyun S, Lugkey K, Imamura A, et al.
J Pharmacol Exp Ther . 2020 Nov; 376(1):136-146. PMID: 33139318
Pulmonary fibrosis remains a serious biomedical problem with no cure and an urgent need for better therapies. Neuraminidases (NEUs), including NEU1, have been recently implicated in the mechanism of pulmonary...
8.
Lee S, Lillehoj H, Chun H, Tuo W, Park H, Cho S, et al.
Nutr Res . 2020 Jul; 27(6):362-366. PMID: 32726895
A variety of different medicinal plants have traditionally been used in Asian cultures as medicinal plants to enhance immunity and treat cancers. However, limited information exists on the underlying mechanisms...
9.
Park I, Oh S, Lillehoj E, Lillehoj H
Front Vet Sci . 2020 Apr; 7:157. PMID: 32266299
Magnolia bark extract administered as a dietary supplement to poultry confers a performance and health benefit, but the mechanisms are unknown. Here, a metabolomics approach was used to identify changes...
10.
Park I, Zimmerman N, Smith A, Rehberger T, Lillehoj E, Lillehoj H
Front Vet Sci . 2020 Mar; 7:123. PMID: 32195276
Direct-fed microbials (DFMs) are dietary supplements containing live microorganisms which confer a performance and health benefit to the host, but the mechanisms are unclear. Here, a metabolomics approach was used...