Erik Knutsen
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Explore the profile of Erik Knutsen including associated specialties, affiliations and a list of published articles.
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34
Citations
918
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Recent Articles
1.
Haugland K, Jordbraek S, Knutsen E, Kjelstrup K, Brun V
eNeuro
. 2025 Feb;
12(2).
PMID: 39900507
Growth hormone (GH) is a neuromodulator that binds to receptors in the hippocampus and alters synaptic plasticity. A decline in GH levels is associated with normal aging, stress, and disease,...
2.
Calina T, Perez E, Grafenhorst E, Benhamida J, Schallenberg S, Popescu A, et al.
Clin Epigenetics
. 2024 Nov;
16(1):156.
PMID: 39523345
Background: We have recently constructed a DNA methylation classifier that can discriminate between pancreatic ductal adenocarcinoma (PAAD) liver metastasis and intrahepatic cholangiocarcinoma (iCCA) with high accuracy (PAAD-iCCA-Classifier). PAAD is one...
3.
Fuentes-Mattei E, Bayraktar R, Manshouri T, Silva A, Ivan C, Gulei D, et al.
JCI Insight
. 2024 Feb;
9(3).
PMID: 38329131
No abstract available.
4.
Knutsen E, Das Sajib S, Fiskaa T, Lorens J, Gudjonsson T, Maelandsmo G, et al.
Front Oncol
. 2023 Dec;
13:1249895.
PMID: 38111531
Epithelial-mesenchymal transition (EMT) is a cellular plasticity program critical for embryonic development and tissue regeneration, and aberrant EMT is associated with disease including cancer. The high degree of plasticity in...
5.
Dragomir M, Fuentes-Mattei E, Winkle M, Okubo K, Bayraktar R, Knutsen E, et al.
J Clin Invest
. 2023 Jun;
133(14).
PMID: 37261908
Sepsis remains a leading cause of death for humans and currently has no pathogenesis-specific therapy. Hampered progress is partly due to a lack of insight into deep mechanistic processes. In...
6.
Drula R, Pardini B, Fu X, Cruz De Los Santos M, Jurj A, Pang L, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(23):e2122053120.
PMID: 37252969
The causes and consequences of abnormal biogenesis of extracellular vesicles (EVs) are not yet well understood in malignancies, including in breast cancers (BCs). Given the hormonal signaling dependence of estrogen...
7.
Untergasser A, Hellemans J, Pfaffl M, Ruijter J, van den Hoff M, Dragomir M, et al.
Mol Oncol
. 2023 Mar;
17(5):713-717.
PMID: 36916500
Accuracy and transparency of scientific data are becoming more and more relevant with the increasing concern regarding the evaluation of data reproducibility in many research areas. This concern is also...
8.
Karagiorgou Z, Fountas P, Manou D, Knutsen E, Theocharis A
Cancers (Basel)
. 2022 Nov;
14(21).
PMID: 36358747
Proteoglycans (PGs) are pivotal components of extracellular matrices, involved in a variety of processes such as migration, invasion, morphogenesis, differentiation, drug resistance, and epithelial-to-mesenchymal transition (EMT). Cellular plasticity is a...
9.
Klec C, Knutsen E, Schwarzenbacher D, Jonas K, Pasculli B, Heitzer E, et al.
Cell Mol Life Sci
. 2022 Jul;
79(7):391.
PMID: 35776213
The RNA-binding protein ALYREF (THOC4) is involved in transcriptional regulation and nuclear mRNA export, though its role and molecular mode of action in breast carcinogenesis are completely unknown. Here, we...
10.
Tellez-Gabriel M, Tekpli X, Reine T, Hegge B, Nielsen S, Chen M, et al.
Front Oncol
. 2022 May;
12:868868.
PMID: 35494005
Serglycin is a proteoglycan highly expressed by immune cells, in which its functions are linked to storage, secretion, transport, and protection of chemokines, proteases, histamine, growth factors, and other bioactive...