George Adrian Calin
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Explore the profile of George Adrian Calin including associated specialties, affiliations and a list of published articles.
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83
Citations
14147
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Recent Articles
1.
Arasi M, De Luca G, Chronopoulou L, Pedini F, Petrucci E, Flego M, et al.
Mol Ther
. 2023 Nov;
32(1):152-167.
PMID: 37990493
Metastatic melanoma poses significant challenges as a highly lethal disease. Despite the success of molecular targeting using BRAF inhibitors (BRAFis) and immunotherapy, the emergence of early recurrence remains an issue...
2.
Pirlog R, Nemeth K, Calin G
Front Endocrinol (Lausanne)
. 2023 Oct;
14:1264302.
PMID: 37822601
No abstract available.
3.
Ichihara M, Takahashi H, Nishida N, Ivan C, Okuzaki D, Yokoyama Y, et al.
Ann Gastroenterol Surg
. 2023 May;
7(3):458-470.
PMID: 37152770
Background: Studies have shown that cancer stemness and the endoplasmic reticulum (ER) stress response are inversely regulated in colorectal cancer (CRC), but the mechanism has not been fully clarified. Long...
4.
Aprile M, Costa V, Cimmino A, Calin G
Int J Cancer
. 2022 Sep;
152(5):822-834.
PMID: 36082440
The view of long noncoding RNAs as nonfunctional "garbage" has been definitely outdated by the large body of evidence indicating this class of ncRNAs as "golden junk", especially in precision...
5.
Fan Y, Li Y, Yao X, Jin J, Scott A, Liu B, et al.
Gut
. 2022 Aug;
72(4):624-637.
PMID: 36002248
Objective: Many cancers engage embryonic genes for rapid growth and evading the immune system. SOX9 has been upregulated in many tumours, yet the role of SOX9 in mediating immunosuppressive tumour...
6.
Cismaru C, Pirlog R, Calin G, Berindan-Neagoe I
Stem Cell Rev Rep
. 2022 Jul;
18(8):2549-2565.
PMID: 35841518
Stem cells are at the basis of tissue homeostasis, hematopoiesis and various regenerative processes. Epigenetic changes in their somatically imprinted genes, prolonged exposure to mutagens/carcinogens or alteration of their niche...
7.
Klec C, Knutsen E, Schwarzenbacher D, Jonas K, Pasculli B, Heitzer E, et al.
Cell Mol Life Sci
. 2022 Jul;
79(7):391.
PMID: 35776213
The RNA-binding protein ALYREF (THOC4) is involved in transcriptional regulation and nuclear mRNA export, though its role and molecular mode of action in breast carcinogenesis are completely unknown. Here, we...
8.
Transcribed Ultraconserved Regions Are Associated with Clinicopathological Features in Breast Cancer
Zambalde E, Adamoski D, Gradia D, Rabinovich I, Rodrigues A, Ivan C, et al.
Biomolecules
. 2022 Feb;
12(2).
PMID: 35204715
Ultraconserved regions (UCRs) are 481 genome segments, with length longer than 200 bp, that are 100% conserved among humans, mice, and rats. The majority of UCRs are transcriptionally active (T-UCRs)...
9.
Pirlog R, Drula R, Nutu A, Calin G, Berindan-Neagoe I
Int J Mol Sci
. 2021 Nov;
22(22).
PMID: 34830370
Colon cancer-associated transcript 2 (CCAT2) is an intensively studied lncRNA with important regulatory roles in cancer. As such, cumulative studies indicate that CCAT2 displays a high functional versatility due to...
10.
Zambalde E, Bayraktar R, Jucoski T, Ivan C, Rodrigues A, Mathias C, et al.
RNA Biol
. 2021 Aug;
18(sup1):416-429.
PMID: 34387142
The human genome contains 481 ultraconserved regions (UCRs), which are genomic stretches of over 200 base pairs conserved among human, rat, and mouse. The majority of these regions are transcriptionally...