Eric M Small
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Explore the profile of Eric M Small including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Cohen E, Yee M, Roethlin K, Prelipcean I, Small E, Porter G, et al.
Am J Physiol Heart Circ Physiol
. 2025 Mar;
PMID: 40047849
Preterm infants exposed to supplemental oxygen (hyperoxia) are at risk for developing heart failure later in life. Exposing rodents in early postnatal life to hyperoxia causes heart failure that resembles...
2.
Venu V, Roth C, Adikari S, Small E, Starkenburg S, Sanbonmatsu K, et al.
Commun Biol
. 2024 Jun;
7(1):721.
PMID: 38862613
The genome folds into complex configurations and structures thought to profoundly impact its function. The intricacies of this dynamic structure-function relationship are not well understood particularly in the context of...
3.
Liu X, Burke R, Lighthouse J, Baker C, Dirkx Jr R, Kang B, et al.
Circ Res
. 2023 Jul;
133(3):271-287.
PMID: 37409456
Background: Cardiomyopathy is characterized by the pathological accumulation of resident cardiac fibroblasts that deposit ECM (extracellular matrix) and generate a fibrotic scar. However, the mechanisms that control the timing and...
4.
Quijada P, Park S, Zhao P, Kolluri K, Wong D, Shih K, et al.
J Clin Invest
. 2023 May;
133(10).
PMID: 37183820
Despite the prevalence of pericytes in the microvasculature of the heart, their role during ischemia-induced remodeling remains unclear. We used multiple lineage-tracing mouse models and found that pericytes migrated to...
5.
Small E, Osley M
FEBS J
. 2023 Mar;
290(14):3539-3562.
PMID: 36871139
Quiescence or G0 is a reversible state in which cells cease division but retain the ability to resume proliferation. Quiescence occurs in all organisms and is essential for stem cell...
6.
Burgos Villar K, Liu X, Small E
Curr Opin Physiol
. 2023 Feb;
28.
PMID: 36777260
Cardiac fibroblasts play critical roles in the maintenance of cardiac structure and the response to cardiac insult. Extracellular matrix deposition by activated resident cardiac fibroblasts, called myofibroblasts, is an essential...
7.
8.
Wu X, Liu H, Brooks A, Xu S, Luo J, Steiner R, et al.
Circ Res
. 2022 Oct;
131(11):926-943.
PMID: 36278398
Background: Heart failure with preserved ejection fraction (HFpEF) is a growing health problem without effective therapies. Epidemiological studies indicate that diabetes is a strong risk factor for HFpEF, and about...
9.
Perez-Hernandez M, van Opbergen C, Bagwan N, Vissing C, Marron-Linares G, Zhang M, et al.
Circulation
. 2022 Aug;
146(11):851-867.
PMID: 35959657
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by high propensity to life-threatening arrhythmias and progressive loss of heart muscle. More than 40% of reported genetic variants linked to ARVC...
10.
Misra A, Baker C, Pritchett E, Burgos Villar K, Ashton J, Small E
J Cardiovasc Dev Dis
. 2022 Jan;
9(1).
PMID: 35050211
The neonatal mammalian heart exhibits a remarkable regenerative potential, which includes fibrotic scar resolution and the generation of new cardiomyocytes. To investigate the mechanisms facilitating heart repair after apical resection...