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Eric M Phillips

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Articles 26
Citations 309
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Recent Articles
1.
Maity R, Dungan O, Perras F, Li J, Liu D, Ren S, et al.
J Am Chem Soc . 2024 Nov; 146(49):34141-34151. PMID: 39579128
Isotopic labeling is a powerful technique extensively used in the pharmaceutical industry. By tracking isotope-labeled molecules, researchers gain unique and invaluable insights into the pharmacokinetics and pharmacodynamics of new drug...
2.
Li J, Lin Q, Dungan O, Fu Y, Ren S, Ruccolo S, et al.
J Am Chem Soc . 2024 Nov; 146(46):31497-31506. PMID: 39514417
Hydrogen isotopically labeled compounds have extensive utility across diverse domains, especially in drug discovery and development. However, synthesis of the labeled compounds with exclusive site selectivity and/or high isotope incorporation...
3.
Phillips E, Brock R
J Fam Psychol . 2024 Aug; 38(8):1201-1213. PMID: 39101933
Although exposure to interparental conflict (IPC) in late childhood and adolescence appears to be a robust risk factor for the development of child psychopathology, less work has examined how very...
4.
Selingo J, Greenwood J, Andrews M, Patel C, Neel A, Pio B, et al.
J Am Chem Soc . 2023 Dec; 146(1):936-945. PMID: 38153812
Methods to synthesize diverse collections of substituted piperidines are valuable due to the prevalence of this heterocycle in pharmaceutical compounds. Here, we present a general strategy to access -(hetero)arylpiperidines using...
5.
Laifer L, Tomaso C, Chang O, Phillips E, James T, Nelson J, et al.
J Adolesc . 2023 May; 95(6):1205-1219. PMID: 37211897
Background: The coronavirus disease 2019 (COVID-19) pandemic has had a global impact on youth mental health, and there is a critical need for research examining individual factors that contribute to...
6.
Phillips E, Brock R, James T, Nelson J, Mason W, Espy K, et al.
J Child Psychol Psychiatry . 2023 Mar; 64(10):1505-1516. PMID: 36872576
Background: Although deprivation has been consistently shown to increase risk for psychopathology through impaired executive control, the unique effects of other dimensions of early adversity, such as unpredictability, on executive...
7.
Phillips E, Brock R, James T, Nelson J, Espy K, Nelson T
J Psychopathol Clin Sci . 2022 Nov; 131(8):817-829. PMID: 36326624
Recent work indicates that a general factor, often referred to as the p-factor, underlies nearly all forms of psychopathology. Although the criterion validity and utility of this general factor have...
8.
Pirnot M, Mao E, Lam Y, Limanto J, Cohen R, Chung C, et al.
Org Lett . 2022 Jul; 24(27):4860-4864. PMID: 35793545
A general and diastereoselective fluorination/glycosylation strategy for the synthesis of 2'-fluorinated nucleosides has been developed. Electrophilic fluorination of a glycal with NFSI provided the 1',2'-difunctionalized furanoside intermediate with high diastereoselectivity....
9.
Fryszkowska A, An C, Alvizo O, Banerjee G, Canada K, Cao Y, et al.
Science . 2022 Jun; 376(6599):1321-1327. PMID: 35709255
The emergence of new therapeutic modalities requires complementary tools for their efficient syntheses. Availability of methodologies for site-selective modification of biomolecules remains a long-standing challenge, given the inherent complexity and...
10.
Benkovics T, Peng F, Phillips E, An C, Bade R, Chung C, et al.
J Am Chem Soc . 2022 Mar; 144(13):5855-5863. PMID: 35333525
As practitioners of organic chemistry strive to deliver efficient syntheses of the most complex natural products and drug candidates, further innovations in synthetic strategies are required to facilitate their efficient...