Cole J Batty
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Explore the profile of Cole J Batty including associated specialties, affiliations and a list of published articles.
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23
Citations
221
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Recent Articles
1.
Nelson C, Podesta M, Gempler M, Lee J, Batty C, Mathenge P, et al.
JCI Insight
. 2025 Mar;
PMID: 40036082
Humoral immunity is orchestrated by follicular helper T (Tfh) cells, which promote cognate B cells to produce high-affinity, protective antibodies. In aged individuals, humoral immunity after vaccination is diminished despite...
2.
Ehrenzeller S, Lukesh N, Stiepel R, Middleton D, Nuzzolo S, Tate A, et al.
RSC Pharm
. 2024 Oct;
1(4):727-741.
PMID: 39415944
Rapamycin (rapa), an immunosuppressive medication, has demonstrated considerable effectiveness in reducing organ transplant rejection and treating select autoimmune diseases. However, the standard oral administration of rapa results in poor bioavailability,...
3.
Roque 3rd J, Lukesh N, Hendy D, Dixon T, Islam M, Ontiveros-Padilla L, et al.
Int J Pharm
. 2024 Apr;
656:124076.
PMID: 38569976
Vaccines represent a pivotal health advancement for preventing infection. However, because carrier systems with repeated administration can invoke carrier-targeted immune responses that diminish subsequent immune responses (e.g., PEG antibodies), there...
4.
Pena E, Batty C, Hendy D, Yang S, Ontiveros-Padilla L, Stiepel R, et al.
Int J Pharm
. 2024 Jan;
652:123836.
PMID: 38266940
The most common influenza vaccines are inactivated viruses produced in chicken eggs, which is a time-consuming production method with variable efficacy due to mismatches of the vaccine strains to the...
5.
Hendy D, Lifshits L, Batty C, Carlock M, Ross T, Mousa J, et al.
Mol Pharm
. 2023 Aug;
20(9):4687-4697.
PMID: 37603310
Current seasonal influenza vaccines are limited in that they need to be reformulated every year in order to account for the constant mutation of the virus. Hemagglutinin (HA) immunogens have...
6.
Batty C, Pena E, Amouzougan E, Moore K, Ainslie K, Bachelder E
Bioconjug Chem
. 2023 Jul;
34(8):1447-1458.
PMID: 37458383
The influenza A virus causes substantial morbidity and mortality worldwide every year and poses a constant threat of an emergent pandemic. Seasonal influenza vaccination strategies fail to provide complete protection...
7.
Ontiveros-Padilla L, Batty C, Hendy D, Pena E, Roque 3rd J, Stiepel R, et al.
Front Immunol
. 2023 Apr;
14:1103765.
PMID: 37033992
Currently licensed vaccine adjuvants offer limited mucosal immunity, which is needed to better combat respiratory infections such as influenza. Mast cells (MCs) are emerging as a target for a new...
8.
Stiepel R, Duggan E, Batty C, Ainslie K
Bioeng Transl Med
. 2023 Mar;
8(2):e10421.
PMID: 36925714
The first publication of micro- and nanotechnology in medicine was in 1798 with the use of the Cowpox virus by Edward Jenner as an attenuated vaccine against Smallpox. Since then,...
9.
Hendy D, Johnson-Weaver B, Batty C, Bachelder E, Abraham S, Staats H, et al.
Int J Pharm
. 2023 Feb;
634:122658.
PMID: 36731641
Recently, there has been increasing interest in the activation of mast cells to promote vaccine efficacy. Several mast cell activating (MCA) compounds have been reported such as M7 and Compound...
10.
Batty C, Lifshits L, Hendy D, Eckshtain-Levi M, Ontiveros-Padilla L, Carlock M, et al.
AAPS J
. 2023 Jan;
25(1):22.
PMID: 36720729
Influenza is a global health concern with millions of infections occurring yearly. Seasonal flu vaccines are one way to combat this virus; however, they are poorly protective against influenza as...