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Eric B Taylor

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Articles 112
Citations 3085
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Recent Articles
11.
Siripoksup P, Cao G, Cluntun A, Maschek J, Pearce Q, Brothwell M, et al.
J Clin Invest . 2024 Apr; 134(11). PMID: 38652544
Carbohydrates and lipids provide the majority of substrates to fuel mitochondrial oxidative phosphorylation. Metabolic inflexibility, defined as an impaired ability to switch between these fuels, is implicated in a number...
12.
Riley M, Mitchell C, Ernst S, Taylor E, Welsh M
Proc Natl Acad Sci U S A . 2024 Feb; 121(9):e2318956121. PMID: 38377207
The drug terazosin (TZ) binds to and can enhance the activity of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1) and can increase ATP levels. That finding prompted studies of TZ...
13.
Rauckhorst A, Vasquez Martinez G, Andrade G, Wen H, Kim J, Simoni A, et al.
Mol Metab . 2023 Dec; 79:101849. PMID: 38056691
Objective: Energy-intensive kidney reabsorption processes essential for normal whole-body function are maintained by tubular epithelial cell metabolism. Although tubular metabolism changes markedly following acute kidney injury (AKI), it remains unclear...
14.
Upton E, Schlievert P, Zhang Y, Rauckhorst A, Taylor E, Radoshevich L
MicroPubl Biol . 2023 Nov; 2023. PMID: 37954520
Glycerol Monolaurate (GML) is a naturally occurring fatty acid monoester with antimicrobial properties. is an agent of bioterrorism known for its unique lipopolysaccharide structure and low immunogenicity. Here we assessed...
15.
Li Q, Zhang Q, Kim Y, Gaddam R, Jacobs J, Bachschmid M, et al.
Nat Commun . 2023 Sep; 14(1):5595. PMID: 37696839
Downregulation of endothelial Sirtuin1 (Sirt1) in insulin resistant states contributes to vascular dysfunction. Furthermore, Sirt1 deficiency in skeletal myocytes promotes insulin resistance. Here, we show that deletion of endothelial Sirt1,...
16.
Buchanan J, Rauckhorst A, Taylor E
bioRxiv . 2023 Jul; PMID: 37502990
Tryptophan is an essential amino acid that is extensively characterized as a regulator of cellular function through its metabolism by indoleamine 2,3-deoxygenase (IDO) into the kynurenine pathway. However, despite decades...
17.
Taylor E
Science . 2023 Jul; 381(6654):125-126. PMID: 37440640
Light alters histone methylation in plants via nuclear α-ketoglutarate dehydrogenase.
18.
Liu S, Taylor E, Richards J
Physiol Biochem Zool . 2023 Jun; 96(3):233-246. PMID: 37278589
AbstractDuring the colonization of freshwater by marine fish, adaptation to hypoosmotic conditions may impact their ability to osmoregulate in seawater. The prickly sculpin () is a euryhaline fish with marine...
19.
Mahr R, Jena S, Nashif S, Nelson A, Rauckhorst A, Rome F, et al.
Sci Rep . 2023 May; 13(1):7387. PMID: 37149697
Cytotrophoblasts fuse to form and renew syncytiotrophoblasts necessary to maintain placental health throughout gestation. During cytotrophoblast to syncytiotrophoblast differentiation, cells undergo regulated metabolic and transcriptional reprogramming. Mitochondria play a critical...
20.
Najt C, Adhikari S, Heden T, Cui W, Gansemer E, Rauckhorst A, et al.
Cell Rep . 2023 Apr; 42(5):112435. PMID: 37104088
Organelle interactions play a significant role in compartmentalizing metabolism and signaling. Lipid droplets (LDs) interact with numerous organelles, including mitochondria, which is largely assumed to facilitate lipid transfer and catabolism....