Erdinc Sezgin
Overview
Explore the profile of Erdinc Sezgin including associated specialties, affiliations and a list of published articles.
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104
Citations
3046
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Recent Articles
1.
Carravilla P, Andronico L, Schlegel J, Urem Y, Sjule E, Ragaller F, et al.
Nat Protoc
. 2025 Feb;
PMID: 39972239
Membrane fluidity is a crucial parameter for cellular physiology. Recent evidence suggests that fluidity varies between cell types and states and in diseases. As membrane fluidity has gradually become an...
2.
Sych T, Gorgens A, Steiner L, Gucluler G, Huge Y, Alamdari F, et al.
Nano Lett
. 2025 Jan;
25(6):2173-2180.
PMID: 39878336
Single particle profiling (SPP) is a unique methodology to study nanoscale bioparticles such as liposomes, lipid nanoparticles, extracellular vesicles, and lipoproteins in a single particle and high throughput manner. The...
3.
Weber F, Axmann M, Sezgin E, Amaro M, Sych T, Hochreiner A, et al.
Membranes (Basel)
. 2024 Dec;
14(12.
PMID: 39728711
The viscoelastic properties of biological membranes are crucial in controlling cellular functions and are determined primarily by the lipids' composition and structure. This work studies these properties by varying the...
4.
Doktorova M, Symons J, Zhang X, Wang H, Schlegel J, Lorent J, et al.
bioRxiv
. 2024 Dec;
PMID: 39713443
Membranes are molecular interfaces that compartmentalize cells to control the flow of nutrients and information. These functions are facilitated by diverse collections of lipids, nearly all of which are distributed...
5.
Oasa S, Sezgin E, Ma Y, Horne D, Radmilovic M, Jovanovic-Talisman T, et al.
Transl Psychiatry
. 2024 Nov;
14(1):477.
PMID: 39582064
Naltrexone (NTX), a homolog of the opiate antidote naloxone, is an orally active long-acting general opioid receptor antagonist used in the treatment of opiate dependence. NTX is also found to...
6.
Weber F, Iskrak S, Ragaller F, Schlegel J, Plochberger B, Sezgin E, et al.
J Cell Sci
. 2024 Sep;
137(20).
PMID: 39258319
Environment-sensitive probes are frequently used in spectral and multi-channel microscopy to study alterations in cell homeostasis. However, the few open-source packages available for processing of spectral images are limited in...
7.
Porebski B, Christ W, Corman A, Haraldsson M, Barz M, Lidemalm L, et al.
Mol Ther
. 2024 Jul;
32(9):3012-3024.
PMID: 38956870
Several viruses hijack various forms of endocytosis in order to infect host cells. Here, we report the discovery of a molecule with antiviral properties that we named virapinib, which limits...
8.
Barbotin A, Billaudeau C, Sezgin E, Carballido-Lopez R
Biophys J
. 2024 Jun;
123(16):2484-2495.
PMID: 38877702
Plasma membrane fluidity is an important phenotypic feature that regulates the diffusion, function, and folding of transmembrane and membrane-associated proteins. In bacterial cells, variations in membrane fluidity are known to...
9.
Wiklander O, Mamand D, Mohammad D, Zheng W, Jawad Wiklander R, Sych T, et al.
Nat Biomed Eng
. 2024 May;
8(11):1453-1468.
PMID: 38769158
Extracellular vesicles (EVs) function as natural delivery vectors and mediators of biological signals across tissues. Here, by leveraging these functionalities, we show that EVs decorated with an antibody-binding moiety specific...
10.
Sommerauer C, Gallardo-Dodd C, Savva C, Hases L, Birgersson M, Indukuri R, et al.
Mol Syst Biol
. 2024 Mar;
20(4):374-402.
PMID: 38459198
Sex-based differences in obesity-related hepatic malignancies suggest the protective roles of estrogen. Using a preclinical model, we dissected estrogen receptor (ER) isoform-driven molecular responses in high-fat diet (HFD)-induced liver diseases...