Emmanuel Bouchaert
Overview
Explore the profile of Emmanuel Bouchaert including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
812
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Recent Articles
11.
Tierny D, Serres F, Segaoula Z, Bemelmans I, Bouchaert E, Petain A, et al.
Clin Cancer Res
. 2015 Jul;
21(23):5314-23.
PMID: 26169968
Purpose: F14512 is a new topoisomerase II inhibitor containing a spermine moiety that facilitates selective uptake by tumor cells and increases topoisomerase II poisoning. F14512 is currently in a phase...
12.
Wawrzyniak M, Pich C, Gross B, Schutz F, Fleury S, Quemener S, et al.
J Allergy Clin Immunol
. 2015 Jan;
135(6):1625-35.e5.
PMID: 25556996
Background: Remodeling of quiescent vessels with increases in permeability, vasodilatation, and edema are hallmarks of inflammatory disorders. Factors involved in this type of remodeling represent potential therapeutic targets. Objectives: We...
13.
Staumont-Salle D, Fleury S, Lazzari A, Molendi-Coste O, Hornez N, Lavogiez C, et al.
J Exp Med
. 2014 May;
211(6):1185-96.
PMID: 24821910
Atopic dermatitis (AD) is a chronic allergic dermatosis characterized by epidermal thickening and dermal inflammatory infiltrates with a dominant Th2 profile during the acute phase, whereas a Th1 profile is...
14.
Cdkn2a/p16Ink4a regulates fasting-induced hepatic gluconeogenesis through the PKA-CREB-PGC1α pathway
Bantubungi K, Hannou S, Caron-Houde S, Vallez E, Baron M, Lucas A, et al.
Diabetes
. 2014 May;
63(10):3199-209.
PMID: 24789920
Type 2 diabetes (T2D) is hallmarked by insulin resistance, impaired insulin secretion, and increased hepatic glucose production. The worldwide increasing prevalence of T2D calls for efforts to understand its pathogenesis...
15.
Oger F, Gheeraert C, Mogilenko D, Benomar Y, Molendi-Coste O, Bouchaert E, et al.
J Clin Endocrinol Metab
. 2014 Apr;
99(8):2821-33.
PMID: 24758184
Context: Obesity is characterized by the excessive accumulation of dysfunctional white adipose tissue (WAT), leading to a strong perturbation of metabolic regulations. However, the molecular events underlying this process are...
16.
Makki K, Taront S, Molendi-Coste O, Bouchaert E, Neve B, Eury E, et al.
PLoS One
. 2014 Apr;
9(4):e92684.
PMID: 24710396
The "mechanistic target of rapamycin" (mTOR) is a central controller of growth, proliferation and/or motility of various cell-types ranging from adipocytes to immune cells, thereby linking metabolism and immunity. mTOR...
17.
Lien F, Berthier A, Bouchaert E, Gheeraert C, Alexandre J, Porez G, et al.
J Clin Invest
. 2014 Feb;
124(3):1037-51.
PMID: 24531544
The nuclear bile acid receptor farnesoid X receptor (FXR) is an important transcriptional regulator of bile acid, lipid, and glucose metabolism. FXR is highly expressed in the liver and intestine...
18.
Berrabah W, Aumercier P, Gheeraert C, Dehondt H, Bouchaert E, Alexandre J, et al.
Hepatology
. 2013 Sep;
59(5):2022-33.
PMID: 24037988
Unlabelled: Bile acid metabolism is intimately linked to the control of energy homeostasis and glucose and lipid metabolism. The nuclear receptor farnesoid X receptor (FXR) plays a major role in...
19.
Devos M, Prawitt J, Staumont-Salle D, Hoste E, Fleury S, Bouchaert E, et al.
J Invest Dermatol
. 2012 Aug;
132(12):2857-60.
PMID: 22931922
No abstract available.
20.
Wouters K, Cudejko C, Gijbels M, Fuentes L, Bantubungi K, Vanhoutte J, et al.
PLoS One
. 2012 Mar;
7(3):e32440.
PMID: 22403661
Objective: A genomic region near the CDKN2A locus, encoding p16(INK4a), has been associated to type 2 diabetes and atherosclerotic vascular disease, conditions in which inflammation plays an important role. Recently,...