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Emily R Mahoney

Explore the profile of Emily R Mahoney including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 279
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Recent Articles
1.
Mahoney E, Boudjelel M, Shavel H, Krzyaniak M, Wasielewski M, Malapit C
J Am Chem Soc . 2025 Jan; 147(2):1381-1386. PMID: 39772556
Recent advances in redox flow batteries have made them a viable option for grid-scale energy storage, however they exhibit low energy density. One way to boost energy density is by...
2.
Seto M, Dumitrescu L, Mahoney E, Sclafani A, De Jager P, Menon V, et al.
Neurobiol Aging . 2023 Mar; 126:25-33. PMID: 36905877
The vascular endothelial growth factor (VEGF) signaling family has been implicated in neuroprotection and clinical progression in Alzheimer's disease (AD). Previous work in postmortem human dorsolateral prefrontal cortex demonstrated that...
3.
Seto M, Weiner R, Dumitrescu L, Mahoney E, Hansen S, Janve V, et al.
Neurobiol Aging . 2022 Jul; 118:66-76. PMID: 35896049
Apolipoprotein E4 (APOE-ε4), the strongest common genetic risk factor for Alzheimer's disease (AD), contributes to worse cognition in older adults. However, many APOE-ε4 carriers remain cognitively normal throughout life, suggesting...
4.
Eissman J, Dumitrescu L, Mahoney E, Smith A, Mukherjee S, Lee M, et al.
Brain . 2022 May; 145(7):2541-2554. PMID: 35552371
Approximately 30% of elderly adults are cognitively unimpaired at time of death despite the presence of Alzheimer's disease neuropathology at autopsy. Studying individuals who are resilient to the cognitive consequences...
5.
Seto M, Mahoney E, Dumitrescu L, Ramanan V, Engelman C, Deming Y, et al.
Brain Commun . 2022 Apr; 4(2):fcac066. PMID: 35425899
Preclinical Alzheimer's disease describes some individuals who harbour Alzheimer's pathologies but are asymptomatic. For this study, we hypothesized that genetic variation may help protect some individuals from Alzheimer's-related neurodegeneration. We...
6.
Schmitthenner H, Barrett T, Beach S, Heese L, Weidman C, Dobson D, et al.
ACS Appl Bio Mater . 2022 Jan; 4(7):5435-5448. PMID: 35006725
A practical, modular synthesis of targeted molecular imaging agents (TMIAs) containing near-infrared dyes for optical molecular imaging (OMI) or chelated metals for magnetic resonance imaging (MRI) and single-photon emission correlation...
7.
Stepler K, Mahoney E, Kofler J, Hohman T, Lopez O, Robinson R
Neurobiol Dis . 2020 Oct; 146:105129. PMID: 33049317
Alzheimer's disease (AD) disproportionately affects certain racial and ethnic subgroups, such as African American/Black and Hispanic adults. Genetic, comorbid, and socioeconomic risk factors contribute to this disparity; however, the molecular...
8.
Ouellette A, Neuner S, Dumitrescu L, Anderson L, Gatti D, Mahoney E, et al.
Cell Rep . 2020 Sep; 32(9):108091. PMID: 32877673
Genetic mechanisms underlying age-related cognitive decline and dementia remain poorly understood. Here, we take advantage of the Diversity Outbred mouse population to utilize quantitative trait loci mapping and identify Dlgap2...
9.
Dumitrescu L, Mahoney E, Mukherjee S, Lee M, Bush W, Engelman C, et al.
Brain . 2020 Aug; 143(8):2561-2575. PMID: 32844198
Approximately 30% of older adults exhibit the neuropathological features of Alzheimer's disease without signs of cognitive impairment. Yet, little is known about the genetic factors that allow these potentially resilient...
10.
Raghavan N, Dumitrescu L, Mormino E, Mahoney E, Lee A, Gao Y, et al.
JAMA Neurol . 2020 Jun; 77(10):1288-1298. PMID: 32568366
Importance: Genetic studies of Alzheimer disease have focused on the clinical or pathologic diagnosis as the primary outcome, but little is known about the genetic basis of the preclinical phase...