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Emily J Mitchell

Explore the profile of Emily J Mitchell including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Miller J, Arrasate M, Brooks E, Libeu C, Legleiter J, Hatters D, et al.
Nat Chem Biol . 2011 Nov; 7(12):925-34. PMID: 22037470
Polyglutamine (polyQ) stretches exceeding a threshold length confer a toxic function to proteins that contain them and cause at least nine neurological disorders. The basis for this toxicity threshold is...
2.
Lotz G, Legleiter J, Aron R, Mitchell E, Huang S, Ng C, et al.
J Biol Chem . 2010 Sep; 285(49):38183-93. PMID: 20864533
Inclusion bodies of aggregated mutant huntingtin (htt) fragments are a neuropathological hallmark of Huntington disease (HD). The molecular chaperones Hsp70 and Hsp40 colocalize to inclusion bodies and are neuroprotective in...