Elysia Roche
Overview
Explore the profile of Elysia Roche including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
22
Followers
0
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Recent Articles
1.
Khoury N, Pizzo M, Discenza C, Joy D, Tatarakis D, Todorov M, et al.
Nat Commun
. 2025 Feb;
16(1):1822.
PMID: 39979268
Blood brain barrier-crossing molecules targeting transferrin receptor (TfR) and CD98 heavy chain (CD98hc) are widely reported to promote enhanced brain delivery of therapeutics. Here, we provide a comprehensive and unbiased...
2.
Thomas S, Roche E, Desai P, Pawlowska N, Bauer D, Gingrich D, et al.
Sci Rep
. 2025 Jan;
15(1):3028.
PMID: 39848945
For individuals at high risk of developing breast cancer, interventions to mitigate this risk include surgical removal of their breasts and ovaries or five years treatment with the anti-estrogen tamoxifen...
3.
Yulyaningsih E, Suh J, Fanok M, Chau R, Solanoy H, Takahashi R, et al.
Elife
. 2024 Sep;
12.
PMID: 39287504
The integrated stress response (ISR) is a conserved pathway in eukaryotic cells that is activated in response to multiple sources of cellular stress. Although acute activation of this pathway restores...
4.
Barker S, Thayer M, Kim C, Tatarakis D, Simon M, Dial R, et al.
Sci Transl Med
. 2024 Aug;
16(760):eadi2245.
PMID: 39141703
Antisense oligonucleotides (ASOs) are promising therapeutics for treating various neurological disorders. However, ASOs are unable to readily cross the mammalian blood-brain barrier (BBB) and therefore need to be delivered intrathecally...
5.
Thomas S, Roche E, Desai P, Pawlowska N, Bauer D, Gingrich D, et al.
Res Sq
. 2023 Nov;
PMID: 37961240
For individuals at high risk of developing breast cancer, interventions to mitigate this risk include surgical removal of their breasts and ovaries or five years treatment with the anti-estrogen tamoxifen...
6.
Chew K, Wells R, Moshkforoush A, Chan D, Lechtenberg K, Tran H, et al.
Nat Commun
. 2023 Sep;
14(1):5516.
PMID: 37679403
No abstract available.
7.
Chew K, Wells R, Moshkforoush A, Chan D, Lechtenberg K, Tran H, et al.
Nat Commun
. 2023 Aug;
14(1):5053.
PMID: 37598178
Brain exposure of systemically administered biotherapeutics is highly restricted by the blood-brain barrier (BBB). Here, we report the engineering and characterization of a BBB transport vehicle targeting the CD98 heavy...
8.
Hicks K, Roche E, Wilkerson J, Lindstrom K
J Am Assoc Lab Anim Sci
. 2021 Nov;
60(6):630-636.
PMID: 34753534
Fenbendazole is a broad-spectrum benzimidazole commonly used in laboratory animal medicine as an anthelmintic for elimination of pinworms. This drug is generally regarded as safe, with minimal side effects. Some...