Elke Duchardt-Ferner
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Explore the profile of Elke Duchardt-Ferner including associated specialties, affiliations and a list of published articles.
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53
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635
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Recent Articles
1.
Neissner K, Frohnapfel C, Keller H, Duchardt-Ferner E, Schneider V, Kamjou Z, et al.
Chembiochem
. 2025 Feb;
:e202400959.
PMID: 39960869
The cyclic dinucleotide c-di-GMP is an important second messenger molecule in bacteria and interacts with a variety of receptor molecules including RNA and protein domains. An important class of c-di-GMP-binding...
2.
Neissner K, Keller H, Kirchner L, Dusterhus S, Duchardt-Ferner E, Averhoff B, et al.
J Biol Chem
. 2024 Nov;
301(1):108041.
PMID: 39615687
c-di-GMP is an important second messenger in bacteria regulating, for example motility, biofilm formation, cell wall biosynthesis, infectivity, and natural transformability. It binds to a multitude of intracellular receptors. This...
3.
Toews S, Wacker A, Faison E, Duchardt-Ferner E, Richter C, Mathieu D, et al.
Nucleic Acids Res
. 2024 Jun;
52(13):7971-7986.
PMID: 38842942
We present the nuclear magnetic resonance spectroscopy (NMR) solution structure of the 5'-terminal stem loop 5_SL1 (SL1) of the SARS-CoV-2 genome. SL1 contains two A-form helical elements and two regions...
4.
Vogele J, Duchardt-Ferner E, Bains J, Knezic B, Wacker A, Sich C, et al.
Nucleic Acids Res
. 2024 May;
52(11):6687-6706.
PMID: 38783391
The single-stranded RNA genome of SARS-CoV-2 is highly structured. Numerous helical stem-loop structures interrupted by mismatch motifs are present in the functionally important 5'- and 3'-UTRs. These mismatches modulate local...
5.
Overbeck J, Vogele J, Nussbaumer F, Duchardt-Ferner E, Kreutz C, Wohnert J, et al.
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
135(23):e202218064.
PMID: 38516132
No abstract available.
6.
Kraus L, Duchardt-Ferner E, Brauchle E, Furbacher S, Kelvin D, Marx H, et al.
Nucleic Acids Res
. 2023 Oct;
51(20):11375-11385.
PMID: 37791877
We herein report the selection and characterization of a new riboswitch dependent on the aminoglycoside tobramycin. Its dynamic range rivals even the tetracycline dependent riboswitch to be the current best...
7.
Vogele J, Hymon D, Martins J, Ferner J, Jonker H, Hargrove A, et al.
Nucleic Acids Res
. 2023 Oct;
51(20):11318-11331.
PMID: 37791874
We present the high-resolution structure of stem-loop 4 of the 5'-untranslated region (5_SL4) of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) genome solved by solution state nuclear magnetic...
8.
Overbeck J, Vogele J, Nussbaumer F, Duchardt-Ferner E, Kreutz C, Wohnert J, et al.
Angew Chem Int Ed Engl
. 2023 Mar;
62(23):e202218064.
PMID: 36970768
The synthetic neomycin-sensing riboswitch interacts with its cognate ligand neomycin as well as with the related antibiotics ribostamycin and paromomycin. Binding of these aminoglycosides induces a very similar ground state...
9.
Vogele J, Duchardt-Ferner E, Kruse H, Zhang Z, Sponer J, Krepl M, et al.
RNA
. 2023 Mar;
29(6):790-807.
PMID: 36868785
Pseudouridine is the most frequently naturally occurring RNA modification, found in all classes of biologically functional RNAs. Compared to uridine, pseudouridine contains an additional hydrogen bond donor group and is...
10.
Duchardt-Ferner E, Ferner J, Furtig B, Hengesbach M, Richter C, Schlundt A, et al.
Angew Chem Int Ed Engl
. 2023 Feb;
62(14):e202217171.
PMID: 36748955
The outbreak of COVID-19 in December 2019 required the formation of international consortia for a coordinated scientific effort to understand and combat the virus. In this Viewpoint Article, we discuss...