Elias R Gerrick
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Explore the profile of Elias R Gerrick including associated specialties, affiliations and a list of published articles.
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11
Citations
744
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Recent Articles
1.
Gerrick E, Howitt M
Trends Microbiol
. 2025 Feb;
PMID: 39952813
The gut microbiota critically influences many aspects of host biology, from nutrient acquisition to immunological function, and is integral to metazoan life. While most microbiome research has focused on bacteria,...
2.
Gerrick E, Zlitni S, West P, Carter M, Mechler C, Olm M, et al.
Cell
. 2023 Dec;
187(1):62-78.e20.
PMID: 38096822
The microbiota influences intestinal health and physiology, yet the contributions of commensal protists to the gut environment have been largely overlooked. Here, we discover human- and rodent-associated parabasalid protists, revealing...
3.
Lind A, McDonald N, Gerrick E, Bhatt A, Pollard K
bioRxiv
. 2023 Dec;
PMID: 38045412
, an obligate host-associated protist, is the most common microbial eukaryote in the human gut and is widely distributed across vertebrate hosts. The evolutionary transition of from its free-living stramenopile...
4.
Gerrick E, DeSchepper L, Mechler C, Joubert L, Dunker F, Colston T, et al.
mBio
. 2023 Nov;
14(6):e0227323.
PMID: 37962346
Environmental factors like climate change and captive breeding can impact the gut microbiota and host health. Therefore, conservation efforts for threatened species may benefit from understanding how these factors influence...
5.
Gerrick E, DeSchepper L, Mechler C, Joubert L, Dunker F, Colston T, et al.
bioRxiv
. 2023 Jun;
PMID: 37292851
Parabasalid protists recently emerged as keystone members of the mammalian microbiota with important effects on their host's health. However, the prevalence and diversity of parabasalids in wild reptiles and the...
6.
Fung C, Fraser L, Barron G, Gologorsky M, Atkinson S, Gerrick E, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(23):e2216908120.
PMID: 37253002
Succinate produced by the commensal protist () stimulates chemosensory tuft cells, resulting in intestinal type 2 immunity. Tuft cells express the succinate receptor SUCNR1, yet this receptor does not mediate...
7.
Gerrick K, Gerrick E, Gupta A, Wheelan S, Yegnasubramanian S, Jaffee E
PLoS One
. 2018 Dec;
13(12):e0208602.
PMID: 30532146
Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. Major advances have occurred in understanding the transcriptional, epigenetic, and functional differences...
8.
Pendi A, Lee Y, Farhan S, Acosta F, Bederman S, Sahyouni R, et al.
J Spine Surg
. 2018 Aug;
4(2):287-294.
PMID: 30069520
Background: Supplemental intrathecal morphine (ITM) represents an option to manage postoperative pain after spine surgery due to ease of administration and ability to confer effective short-term analgesia at low dosages....
9.
Gerrick E, Barbier T, Chase M, Xu R, Francois J, Lin V, et al.
Proc Natl Acad Sci U S A
. 2018 Jun;
115(25):6464-6469.
PMID: 29871950
One key to the success of as a pathogen is its ability to reside in the hostile environment of the human macrophage. Bacteria adapt to stress through a variety of...
10.
Rock J, Hopkins F, Chavez A, Diallo M, Chase M, Gerrick E, et al.
Nat Microbiol
. 2017 Feb;
2:16274.
PMID: 28165460
The development of new drug regimens that allow rapid, sterilizing treatment of tuberculosis has been limited by the complexity and time required for genetic manipulations in Mycobacterium tuberculosis. CRISPR interference...