Edwin M Meyer
Overview
Explore the profile of Edwin M Meyer including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
984
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Recent Articles
1.
Thinschmidt J, Lopez-Hernandez G, Ren K, King M, Meyer E, Papke R
Brain Res
. 2008 Mar;
1203:51-60.
PMID: 18321476
One approach to treatment of negative cognitive effects associated with Alzheimer's disease and schizophrenia may involve activation of neuronal alpha7 nicotinic acetylcholine receptors (nAChRs). We used the alpha7-selective partial agonist...
2.
Mocchetti I, Nosheny R, Tanda G, Ren K, Meyer E
Ann N Y Acad Sci
. 2007 Dec;
1122:144-54.
PMID: 18077570
Human immunodeficiency virus type 1 (HIV-1) causes neuronal degeneration and, at a late stage, creates HIV-associated dementia (HAD) and other neurological abnormalities. Therefore, the need for neuroprotective agents is great....
3.
Hirko A, Meyer E, King M, Hughes J
Mol Ther
. 2007 Jul;
15(9):1623-9.
PMID: 17609655
The accumulation and deposition of the 40-42-amino acid peptide amyloid beta (Abeta) is thought to be a critical event in the pathology of Alzheimer's disease (AD). Both passive and active...
4.
Nosheny R, Ahmed F, Yakovlev A, Meyer E, Ren K, Tessarollo L, et al.
Eur J Neurosci
. 2007 Apr;
25(8):2275-84.
PMID: 17445226
Glycoprotein 120 (gp120) from the T-tropic strain of the human immunodeficiency virus type 1 has been shown to cause neuronal apoptosis through activation of the chemokine receptor CXCR4. Therefore, reducing...
5.
Gong Y, Meyer E, Meyers C, Klein R, King M, Hughes J
Exp Neurol
. 2006 Jun;
200(2):371-7.
PMID: 16780838
The gene encoding for the Swedish double mutation (K595N/M596L) of amyloid precursor protein (APP695Swe) was expressed bilaterally in adult rat hippocampus to determine its long-term effects on memory-related behavior as...
6.
Wu K, Meyer E, Bennett J, Meyers C, Hughes J, King M
Brain Res
. 2005 Oct;
1061(2):107-13.
PMID: 16226726
Nerve growth factor (NGF) therapy has been proposed to treat cognitive impairments in aged patients including those with Alzheimer's disease. Various viral vectors, including adeno-associated virus serotype 2 (AAV2), have...
7.
Placzek A, Grassi F, Meyer E, Papke R
Mol Pharmacol
. 2005 Sep;
68(6):1863-76.
PMID: 16186249
The alpha7-type nicotinic acetylcholine receptor (nAChR) has been recognized as a potential therapeutic target for the treatment of a variety of pathologic conditions, including schizophrenia, Alzheimer's disease, and peripheral inflammation....
8.
Thinschmidt J, Frazier C, King M, Meyer E, Papke R
Neurosci Lett
. 2005 Aug;
389(3):163-8.
PMID: 16112453
The medial septum-diagonal band (MS/DB) contains primarily cholinergic and GABAergic neurons that project to the hippocampus, and are important for learning and memory. Whole-cell patch clamp methods with brain slices...
9.
Thinschmidt J, Frazier C, King M, Meyer E, Papke R
Exp Neurol
. 2005 Jul;
195(2):342-52.
PMID: 16000197
The hippocampus receives substantial input from the medial septum/diagonal band of broca (MS/DB) via the fibria-fornix (FF). Projections from the MS/DB innervate hippocampal interneurons that express alpha7 nicotinic receptors and...
10.
Ren K, Puig V, Papke R, Itoh Y, Hughes J, Meyer E
J Neurochem
. 2005 Jun;
94(4):926-33.
PMID: 15969741
alpha7 Nicotinic receptors are calcium permeant and provide neuroprotection against many insults. We investigated the roles of intracellular calcium ions and downstream calcium channels in this protection. The alpha7 agonist...