Jeffrey S Thinschmidt
Overview
Explore the profile of Jeffrey S Thinschmidt including associated specialties, affiliations and a list of published articles.
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25
Citations
500
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Recent Articles
1.
Thinschmidt J, Harden S, King M, Talton J, Frazier C
Front Cell Neurosci
. 2022 Dec;
16:1066312.
PMID: 36479275
We established a novel brain slice assay to test the ability of acetylcholinesterase (AChE) reactivators to prevent ACh-induced M1 muscarinic acetylcholine receptor (mAChR) dependent hyperexcitability observed after exposure to the...
2.
Kumar A, Thinschmidt J, Foster T
Aging (Albany NY)
. 2019 Jul;
11(14):5140-5157.
PMID: 31339863
We examined the contribution of N-methyl-D-aspartate receptor (NMDAR) subunits in the redox-mediated decline in NMDAR function during aging. GluN2A and GluN2B selective antagonists decreased peak NMDAR currents to a similar...
3.
Tan Y, Singhal S, Harden S, Cahill K, Nguyen D, Colon-Perez L, et al.
J Neurosci
. 2019 Feb;
39(17):3249-3263.
PMID: 30804095
Social recognition, the ability to recognize individuals that were previously encountered, requires complex integration of sensory inputs with previous experience. Here, we use a variety of approaches to discern how...
4.
Bhatwadekar A, Duan Y, Korah M, Thinschmidt J, Hu P, Leley S, et al.
Vision Res
. 2017 Oct;
139:211-220.
PMID: 29042190
The widespread nature of diabetes affects all organ systems of an individual including the bone marrow. Long-term damage to the cellular and extracellular components of the bone marrow leads to...
5.
Beli E, Dominguez 2nd J, Hu P, Thinschmidt J, Caballero S, Li Calzi S, et al.
J Mol Med (Berl)
. 2017 Apr;
95(5):565-566.
PMID: 28421250
No abstract available.
6.
Beli E, Dominguez 2nd J, Hu P, Thinschmidt J, Caballero S, Li Calzi S, et al.
J Mol Med (Berl)
. 2016 Jun;
94(11):1255-1265.
PMID: 27344677
Key Messages: • CX3CR1 deletion in STZ-diabetic mice accelerated the onset of diabetic retinopathy (DR). • The early onset of DR was associated with increased retinal cell apoptosis. • The...
7.
Thinschmidt J, Colon-Perez L, Febo M, Caballero S, King M, White F, et al.
Neurosci Lett
. 2016 Jan;
615:21-7.
PMID: 26777426
We recently found indicators of hypothalamic inflammation and neurodegeneration linked to the loss of neuroprotective factors including insulin-like growth factor (IGF-1) and IGF binding protein-2 (IGFBP-3) in mice made diabetic...
8.
Thinschmidt J, King M, Korah M, Perez P, Febo M, Miyan J, et al.
Immunology
. 2015 May;
146(2):206-16.
PMID: 25967648
This study tested the hypothesis that peripheral immune challenges will produce predictable activation patterns in the rat brain consistent with sympathetic excitation. As part of examining this hypothesis, this study...
9.
Hu P, Thinschmidt J, Caballero S, Adamson S, Cole L, Chan-Ling T, et al.
Am J Physiol Endocrinol Metab
. 2015 Feb;
308(8):E688-98.
PMID: 25714673
Neuroinflammation and neurodegeneration have been observed in the brain in type 1 diabetes (T1D). However, little is known about the mediators of these effects. In T1D mice with 12- and...
10.
Moldthan H, Hirko A, Thinschmidt J, Grant M, Li Z, Peris J, et al.
J Stroke Cerebrovasc Dis
. 2014 Mar;
23(5):e355-63.
PMID: 24582784
Our objective is to develop a new therapy for the treatment of stroke. Currently, the only effective therapy for acute ischemic stroke is the thrombolytic agent recombinant tissue plasminogen activator....