Edward N Pugh Jr
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Explore the profile of Edward N Pugh Jr including associated specialties, affiliations and a list of published articles.
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78
Citations
4439
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Recent Articles
1.
Pandiyan V, Nguyen P, Pugh Jr E, Sabesan R
Proc Natl Acad Sci U S A
. 2022 Sep;
119(39):e2202485119.
PMID: 36122241
Human cone outer segment (COS) length changes in response to stimuli bleaching up to 99% of L- and M-cone opsins were measured with high resolution, phase-resolved optical coherence tomography (OCT)....
2.
Meleppat R, Ronning K, Karlen S, Burns M, Pugh Jr E, Zawadzki R
Sci Rep
. 2021 Aug;
11(1):16252.
PMID: 34376700
Melanosomes, lipofuscin, and melanolipofuscin are the three principal types of pigmented granules found in retinal pigment epithelium (RPE) cells. Changes in the density of melanosomes and lipofuscin in RPE cells...
3.
Meleppat R, Ronning K, Karlen S, Kothandath K, Burns M, Pugh Jr E, et al.
Invest Ophthalmol Vis Sci
. 2020 Nov;
61(13):1.
PMID: 33137194
Purpose: To investigate the major organelles of the retinal pigment epithelium (RPE) in wild-type (WT, control) mice and their changes in pigmented Abca4 knockout (Abca4-/-) mice with in situ morphologic,...
4.
Zhang P, Shibata B, Peinado G, Zawadzki R, FitzGerald P, Pugh Jr E
Invest Ophthalmol Vis Sci
. 2020 Mar;
61(3):9.
PMID: 32176260
Purpose: To investigate diurnal variation in the length of mouse rod outer segments in vivo. Methods: The lengths of rod inner and outer segments (RIS, ROS) of dark-adapted albino mice...
5.
Zhang P, Miller E, Manna S, Meleppat R, Pugh Jr E, Zawadzki R
Neurophotonics
. 2019 Sep;
6(4):041105.
PMID: 31528657
It has been recently demonstrated that structures corresponding to the cell bodies of highly transparent cells in the retinal ganglion cell layer could be visualized noninvasively in the living human...
6.
Miller E, Zhang P, Ching K, Pugh Jr E, Burns M
Proc Natl Acad Sci U S A
. 2019 Jul;
116(33):16603-16612.
PMID: 31350349
Microglia respond to damage and microenvironmental changes within the central nervous system by morphologically transforming and migrating to the lesion, but the real-time behavior of populations of these resident immune...
7.
8.
Zhang P, Manna S, Miller E, Jian Y, Meleppat R, Sarunic M, et al.
Biomed Opt Express
. 2019 Feb;
10(2):552-570.
PMID: 30800499
Speckle is an inevitable consequence of the use of coherent light in imaging and acts as noise that corrupts image formation in most applications. Optical coherence tomographic imaging, as a...
9.
Goswami M, Wang X, Zhang P, Xiao W, Karlen S, Li Y, et al.
Biomed Opt Express
. 2019 Feb;
10(1):151-166.
PMID: 30775090
In cancer research there is a fundamental need for animal models that allow the longitudinal visualization and quantification of tumor development, nanotherapeutic delivery, the tumor microenvironment including blood vessels, macrophages,...
10.
Zhang P, Mocci J, Wahl D, Meleppat R, Manna S, Quintavalla M, et al.
Exp Eye Res
. 2018 Apr;
172:86-93.
PMID: 29604280
For in vivo mouse retinal imaging, especially with Adaptive Optics instruments, application of a contact lens is desirable, as it allows maintenance of cornea hydration and helps to prevent cataract...