Edward Macarak
Overview
Explore the profile of Edward Macarak including associated specialties, affiliations and a list of published articles.
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10
Citations
325
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Recent Articles
1.
Basta M, Petruk S, Summer R, Rosenbloom J, Wermuth P, Macarak E, et al.
iScience
. 2023 May;
26(5):106570.
PMID: 37250334
Cell reprogramming to a myofibroblast responsible for the pathological accumulation of extracellular matrix is fundamental to the onset of fibrosis. Here, we explored how condensed chromatin structure marked by H3K72me3...
2.
Rosenbloom J, Macarak E, Piera-Velazquez S, Jimenez S
Methods Mol Biol
. 2017 Aug;
1627:1-23.
PMID: 28836191
Human fibrotic diseases constitute a major health problem worldwide owing to the large number of affected individuals, the incomplete knowledge of the fibrotic process pathogenesis, the marked heterogeneity in their...
3.
Andrews J, Marttala J, Macarak E, Rosenbloom J, Uitto J
Matrix Biol
. 2016 Feb;
51:37-46.
PMID: 26844756
Keloids, fibroproliferative dermal tumors with effusive accumulation of extracellular matrix (ECM) components, particularly collagen, result from excessive expression of growth factors and cytokines. The etiology of keloids is unknown but...
4.
Jin X, Ren S, Macarak E, Rosenbloom J
Matrix Biol
. 2016 Jan;
51:55-64.
PMID: 26825317
Peritoneal adhesions, primarily caused by surgical procedures, are the leading cause of pelvic pain, bowel obstruction, and infertility. TGF-β1 and IL-6 have been found to be elevated in the peritoneal...
5.
Rosenbloom J, Ren S, Macarak E
Matrix Biol
. 2016 Jan;
51:14-25.
PMID: 26807756
Fibrotic diseases constitute a world-wide major health problem, but research support remains inadequate in comparison to the need. Although considerable understanding of the pathogenesis of fibrotic reactions has been attained,...
6.
Andrews J, Marttala J, Macarak E, Rosenbloom J, Uitto J
J Invest Dermatol
. 2015 Feb;
135(7):1921-1924.
PMID: 25685931
No abstract available.
7.
Han J, Macarak E, Rosenbloom J, Chung K, Chaqour B
Eur J Biochem
. 2003 Aug;
270(16):3408-21.
PMID: 12899698
Cysteine-rich protein 61 (Cyr61/CCN1) is an angiogenic factor and a member of a family of growth factor-inducible immediate-early genes with functions in cell adhesion, proliferation and differentiation. We investigated the...
8.
Chaqour B, Whitbeck C, Han J, Macarak E, Horan P, Chichester P, et al.
Am J Physiol Endocrinol Metab
. 2002 Sep;
283(4):E765-74.
PMID: 12217894
Cysteine-rich protein (Cyr61) and connective tissue growth factor (CTGF) are key immediate early growth factors with functions in cell proliferation, differentiation, and extracellular matrix synthesis. Studies were performed to assess...
9.
Meneveau N, Klugherz B, Chaqour B, Anand V, Tomaszewski J, Joullie M, et al.
Coron Artery Dis
. 2002 Jul;
13(3):189-97.
PMID: 12131024
Background: Neointimal formation is a major cause of restenosis after interventional vascular procedures. Beta-cyclodextrin tetradecasulfate (beta-CDT) has been shown to inhibit fibroblast growth factor activity and we hypothesized that beta-CDT...
10.
Chaqour B, Han J, Tamura I, Macarak E
J Cell Biochem
. 2002 Jan;
84(2):264-77.
PMID: 11787055
Mechanical forces are well known to modulate smooth muscle cell growth and synthetic phenotype. The signals controlling this process are complex and potentially involve changes in the expression of peptide...