Brahim Chaqour
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Explore the profile of Brahim Chaqour including associated specialties, affiliations and a list of published articles.
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54
Citations
989
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Recent Articles
1.
ONeill N, Khan R, Abd Alhadi S, Dine K, Geisler J, Chaqour B, et al.
Biomolecules
. 2025 Feb;
15(2).
PMID: 40001492
Optic neuritis is an inflammatory demyelinating disease of the optic nerve that often occurs in multiple sclerosis (MS) patients. Sixty percent of patients develop some level of permanent visual loss...
2.
Chaqour B
J Cell Commun Signal
. 2025 Feb;
19(1):e70000.
PMID: 39958276
I am deeply honored to have been appointed as the new Editor-in-Chief (EiC) of the (). As I step into this role of EiC, I look forward to continuing collaborating...
3.
Kwok A, Chaqour B, Khan R, Aravand P, Dine K, Ross A, et al.
Transl Vis Sci Technol
. 2024 Sep;
13(9):27.
PMID: 39330985
Purpose: Resveratrol (RSV) is a nutraceutical compound known for its therapeutic potential in neurodegenerative and metabolic diseases. RSV promotes survival signals in retinal ganglion cells (RGCs) through activation of SIRT1,...
4.
ONeill N, Meng M, Chaqour B, Dine K, Sarabu N, Pham J, et al.
Transl Vis Sci Technol
. 2024 Aug;
13(8):37.
PMID: 39177995
Purpose: Adeno-associated virus (AAV) demonstrates promise in delivering therapeutic genes to retinal ganglion cells (RGCs). Delivery of neuroprotective genes is constrained by packaging size and/or cell selectivity. This study compares...
5.
Meng M, Chaqour B, ONeill N, Dine K, Sarabu N, Ying G, et al.
Invest Ophthalmol Vis Sci
. 2024 Apr;
65(4):19.
PMID: 38587440
Purpose: Retinal ganglion cell (RGC) loss provides the basis for diagnosis and stage determination of many optic neuropathies, and quantification of RGC survival is a critical outcome measure in models...
6.
Chaqour B, Duong T, Yue J, Liu T, Camacho D, Dine K, et al.
Gene Ther
. 2024 Jan;
31(3-4):175-186.
PMID: 38200264
Recombinant adeno-associated virus (AAV)-2 has significant potential as a delivery vehicle of therapeutic genes to retinal ganglion cells (RGCs), which are key interventional targets in optic neuropathies. Here we show...
7.
Camacho D, Go C, Chaqour B, Shindler K, Ross A
J Neuroophthalmol
. 2023 Jul;
43(3):330-340.
PMID: 37440418
Optic neuropathies encompass a breadth of diseases that ultimately result in dysfunction and/or loss of retinal ganglion cells (RGCs). Although visual impairment from optic neuropathies is common, there is a...
8.
Chaqour B
J Cell Commun Signal
. 2023 May;
17(2):255-262.
PMID: 37191840
The retina is a highly specialized tissue composed of a network of neurons, glia, and vascular and epithelial cells; all working together to coordinate and transduce visual signals to the...
9.
Yue J, Khan R, Duong T, Dine K, Cui Q, ONeill N, et al.
Neurotherapeutics
. 2023 Mar;
20(3):896-907.
PMID: 36941497
SIRT1 prevents retinal ganglion cell (RGC) loss in several acute and subacute optic neuropathy models following pharmacologic activation or genetic overexpression. We hypothesized that adeno-associated virus (AAV)-mediated overexpression of SIRT1...
10.
Attramadal H, Banerjee S, Chaqour B, Fisher G, Lau L, Perbal B, et al.
J Cell Commun Signal
. 2023 Feb;
17(1):7-11.
PMID: 36790605
In celebration of the twentieth anniversary of the inception of the CCN society, and of the first post-Covid-19 live meeting, the executive board of the ICCNS had chosen Nice as...