Edward Leithe
Overview
Explore the profile of Edward Leithe including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
1306
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Recent Articles
1.
Totland M, Knudsen L, Rasmussen N, Omori Y, Sorensen V, Elster V, et al.
Cell Mol Life Sci
. 2024 Apr;
81(1):171.
PMID: 38597989
Intercellular communication via gap junctions has a fundamental role in regulating cell growth and tissue homeostasis, and its dysregulation may be involved in cancer development and radio- and chemotherapy resistance....
2.
Totland M, Omori Y, Sorensen V, Kryeziu K, Aasen T, Brech A, et al.
Biochim Biophys Acta Mol Basis Dis
. 2023 Jul;
1869(7):166812.
PMID: 37454772
Gap junctions are specialized regions of the plasma membrane containing clusters of channels that provide for the diffusion of ions and small molecules between adjacent cells. A fundamental role of...
3.
Totland M, Rasmussen N, Knudsen L, Leithe E
Cell Mol Life Sci
. 2019 Sep;
77(4):573-591.
PMID: 31501970
Gap junctions consist of arrays of intercellular channels that enable adjacent cells to communicate both electrically and metabolically. Gap junctions have a wide diversity of physiological functions, playing critical roles...
4.
Aasen T, Leithe E, Graham S, Kameritsch P, Mayan M, Mesnil M, et al.
Oncogene
. 2019 Mar;
38(23):4429-4451.
PMID: 30814684
Gap junctions comprise arrays of intercellular channels formed by connexin proteins and provide for the direct communication between adjacent cells. This type of intercellular communication permits the coordination of cellular...
5.
Totland M, Bergsland C, Fykerud T, Knudsen L, Rasmussen N, Eide P, et al.
J Cell Sci
. 2017 Jul;
130(17):2867-2882.
PMID: 28733455
Intercellular communication via gap junctions has an important role in controlling cell growth and in maintaining tissue homeostasis. Connexin 43 (Cx43; also known as GJA1) is the most abundantly expressed...
6.
Mesnil M, Aasen T, Boucher J, Chepied A, Cronier L, Defamie N, et al.
Biochim Biophys Acta Biomembr
. 2017 Jun;
1860(1):237-243.
PMID: 28655619
This article is a report of the "International Colloquium on Gap junctions: 50Years of Impact on Cancer" that was held 8-9 September 2016, at the Amphitheater "Pôle Biologie Santé" of...
7.
Sveen A, Johannessen B, Tengs T, Danielsen S, Eilertsen I, Lind G, et al.
Genome Med
. 2017 May;
9(1):46.
PMID: 28539123
Background: Approximately 15% of primary colorectal cancers have DNA mismatch repair deficiency, causing a complex genome with thousands of small mutations-the microsatellite instability (MSI) phenotype. We investigated molecular heterogeneity and...
8.
Leithe E, Mesnil M, Aasen T
Biochim Biophys Acta Biomembr
. 2017 May;
1860(1):48-64.
PMID: 28526583
Connexins are chordate gap junction channel proteins that, by enabling direct communication between the cytosols of adjacent cells, create a unique cell signalling network. Gap junctional intercellular communication (GJIC) has...
9.
Dukic A, Haugen L, Pidoux G, Leithe E, Bakke O, Tasken K
Cell Signal
. 2017 Jan;
32:1-11.
PMID: 28077322
Communication between adjacent cells can occur via gap junctions (GJ) composed of connexin (Cx) hexamers that allow passage of small molecules. One of the most widely and highly expressed Cxs...
10.
Fykerud T, Knudsen L, Totland M, Sorensen V, Dahal-Koirala S, Lothe R, et al.
Cell Cycle
. 2016 Sep;
15(21):2943-2957.
PMID: 27625181
In order to achieve accurate chromosome segregation, eukaryotic cells undergo a dramatic change in morphology to obtain a spherical shape during mitosis. Interphase cells communicate directly with each other by...