Edward J Murray
Overview
Explore the profile of Edward J Murray including associated specialties, affiliations and a list of published articles.
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10
Citations
109
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Recent Articles
1.
Gorlitz F, Kelly D, Warren S, Alibhai D, West L, Kumar S, et al.
J Vis Exp
. 2017 Feb;
(119).
PMID: 28190060
We present an open source high content analysis instrument utilizing automated fluorescence lifetime imaging (FLIM) for assaying protein interactions using Förster resonance energy transfer (FRET) based readouts of fixed or...
2.
Fullen D, Murray B, Mori J, Catchpole A, Borley D, Murray E, et al.
PLoS One
. 2016 Dec;
11(12):e0166113.
PMID: 27936016
Background: Human Rhinovirus infection is an important precursor to asthma and chronic obstructive pulmonary disease exacerbations and the Human Viral Challenge model may provide a powerful tool in studying these...
3.
Fullen D, Noulin N, Catchpole A, Fathi H, Murray E, Mann A, et al.
PLoS One
. 2016 Jun;
11(6):e0157211.
PMID: 27280602
[This corrects the article DOI: 10.1371/journal.pone.0145902.].
4.
Fullen D, Noulin N, Catchpole A, Fathi H, Murray E, Mann A, et al.
PLoS One
. 2016 Jan;
11(1):e0145902.
PMID: 26761707
Background: Influenza and its associated diseases are a major cause of morbidity and mortality. The United States Advisory Committee on Immunization Practices recommends influenza vaccination for everyone over 6 months...
5.
Kelly G, Laxton C, Garelnabi M, Alton B, Addan F, Catchpole A, et al.
J Virol Methods
. 2015 Sep;
224:83-90.
PMID: 26335961
Retroscreen (hVIVO) have developed an RSV human viral challenge model (hVCM) for testing the efficacy of novel antiviral therapies by monitoring changes in viral load and symptoms. The integrated cycler...
6.
Pryde D, Tran T, Gardner I, Bright H, Stupple P, Galan S, et al.
Bioorg Med Chem Lett
. 2012 Dec;
23(3):827-33.
PMID: 23265891
Several non-benzimidazole containing inhibitors of respiratory syncytial virus are described. Core template modification, analysis of antiviral activity, physicochemistry and optimisation of properties led to the thiazole-imidazole 13, that showed a...
7.
Alibhai D, Kelly D, Warren S, Kumar S, Margineau A, Serwa R, et al.
J Biophotonics
. 2012 Nov;
6(5):398-408.
PMID: 23184449
Fluorescence lifetime measurements can provide quantitative readouts of local fluorophore environment and can be applied to biomolecular interactions via Förster resonant energy transfer (FRET). Fluorescence lifetime imaging (FLIM) can therefore...
8.
Kumar S, Alibhai D, Margineanu A, Laine R, Kennedy G, Mcginty J, et al.
Chemphyschem
. 2011 Feb;
12(3):609-26.
PMID: 21337485
A fluorescence lifetime imaging (FLIM) technology platform intended to read out changes in Förster resonance energy transfer (FRET) efficiency is presented for the study of protein interactions across the drug-discovery...
9.
Bannister R, Rodrigues D, Murray E, Laxton C, Westby M, Bright H
Virol J
. 2010 Sep;
7:250.
PMID: 20860795
Background: The BALB/c mouse is commonly used to study RSV infection and disease. However, despite the many advantages of this well-characterised model, the inoculum is large, viral replication is restricted...
10.
Murray E, Leaman D, Pawa N, Perkins H, Pickford C, Perros M, et al.
J Virol
. 2010 Apr;
84(14):7288-99.
PMID: 20427524
A low-molecular-weight human immunodeficiency virus type 1 (HIV-1) inhibitor, PF-68742 (molecular weight, 573), has been identified in a high-throughput screen for compounds that block HIV-1 envelope glycoprotein (Env)-mediated fusion. The...