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Andrew Catchpole

Explore the profile of Andrew Catchpole including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 177
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Recent Articles
1.
Rosenheim J, Gupta R, Thakker C, Mann T, Bell L, Broderick C, et al.
Nat Commun . 2024 Nov; 15(1):10434. PMID: 39616162
Blood transcriptional biomarkers of acute viral infections typically reflect type 1 interferon (IFN) signalling, but it is not known whether there are biological differences in their regulation that can be...
2.
Lindeboom R, Worlock K, Dratva L, Yoshida M, Scobie D, Wagstaffe H, et al.
Nature . 2024 Aug; 632(8025):E3. PMID: 39090314
No abstract available.
3.
Lindeboom R, Worlock K, Dratva L, Yoshida M, Scobie D, Wagstaffe H, et al.
Nature . 2024 Jun; 631(8019):189-198. PMID: 38898278
The COVID-19 pandemic is an ongoing global health threat, yet our understanding of the dynamics of early cellular responses to this disease remains limited. Here in our SARS-CoV-2 human challenge...
4.
Jackson S, Marshall J, Mawer A, Lopez-Ramon R, Harris S, Satti I, et al.
Lancet Microbe . 2024 May; 5(7):655-668. PMID: 38703782
Background: A SARS-CoV-2 controlled human infection model (CHIM) has been successfully established in seronegative individuals using a dose of 1×10 50% tissue culture infectious dose (TCID) pre-alpha SARS-CoV-2 virus. Given...
5.
Marchal A, Cirulli E, Neveux I, Bellos E, Thwaites R, Schiabor Barrett K, et al.
HGG Adv . 2024 Apr; 5(3):100300. PMID: 38678364
Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an association between the HLA-B∗15:01 allele and asymptomatic...
6.
Wagstaffe H, Thwaites R, Reynaldi A, Sidhu J, McKendry R, Ascough S, et al.
Sci Immunol . 2024 Feb; 9(92):eadj9285. PMID: 38335268
Human infection challenge permits in-depth, early, and pre-symptomatic characterization of the immune response, enabling the identification of factors that are important for viral clearance. Here, we performed intranasal inoculation of...
7.
Marchal A, Cirulli E, Neveux I, Bellos E, Thwaites R, Schiabor Barrett K, et al.
medRxiv . 2024 Jan; PMID: 38168184
Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an association between the HLA-B*15:01 allele and asymptomatic...
8.
Schmoele-Thoma B, Zareba A, Jiang Q, Maddur M, Danaf R, Mann A, et al.
N Engl J Med . 2022 Jun; 386(25):2377-2386. PMID: 35731653
Background: Although human respiratory syncytial virus (RSV) is an important cause of illness and death in older adults, no RSV vaccine has been licensed. Methods: In a phase 2a study,...
9.
Rapeport G, Smith E, Gilbert A, Catchpole A, McShane H, Chiu C
N Engl J Med . 2021 Jul; 385(11):961-964. PMID: 34289273
No abstract available.
10.
Lambkin-Williams R, Noulin N, Mann A, Catchpole A, Gilbert A
Respir Res . 2018 Jun; 19(1):123. PMID: 29929556
The Human Viral Challenge (HVC) model has, for many decades, helped in the understanding of respiratory viruses and their role in disease pathogenesis. In a controlled setting using small numbers...