Edward F Srour
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Explore the profile of Edward F Srour including associated specialties, affiliations and a list of published articles.
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92
Citations
2914
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Recent Articles
11.
Trinh T, Ropa J, Aljoufi A, Cooper S, Sinn A, Srour E, et al.
Leukemia
. 2020 Nov;
35(7):2064-2075.
PMID: 33159180
The hematopoietic system is sustained by a rare population of hematopoietic stem cells (HSCs), which emerge during early embryonic development and then reside in the hypoxic niche of the adult...
12.
Kanagasabapathy D, Blosser R, Maupin K, Hong J, Alvarez M, Ghosh J, et al.
Aging (Albany NY)
. 2020 Jul;
12(14):15121-15133.
PMID: 32634116
Megakaryocytes (MKs) support bone formation by stimulating osteoblasts (OBs) and inhibiting osteoclasts (OCs). Aging results in higher bone resorption, leading to bone loss. Whereas previous studies showed the effects of...
13.
Maupin K, Himes E, Plett A, Chua H, Singh P, Ghosh J, et al.
Bone
. 2019 Jul;
127:452-459.
PMID: 31299382
Osteoblast number and activity decreases with aging, contributing to the age-associated decline of bone mass, but the mechanisms underlying changes in osteoblast activity are not well understood. Here, we show...
14.
Zhang J, Ghosh J, Mohamad S, Zhang C, Huang X, Capitano M, et al.
Stem Cells
. 2019 Jul;
37(10):1319-1330.
PMID: 31260147
Hematopoietic stem (HSC) and progenitor (HPC) cells are regulated by interacting signals and cellular and noncellular elements of the hematopoietic niche. We previously showed that CD166 is a functional marker...
15.
Soonpaa M, Lafontant P, Reuter S, Scherschel J, Srour E, Zaruba M, et al.
Circulation
. 2018 Dec;
138(25):2963-2966.
PMID: 30566013
No abstract available.
16.
Ghosh J, Mohamad S, Srour E
Methods Mol Biol
. 2018 Dec;
2002:181-193.
PMID: 30539348
Hematopoietic stem cells (HSCs) are regulated by multiple components of the hematopoietic niche, including bone marrow-derived macrophages and osteomacs. However, both macrophages and osteomacs are phenotypically similar. Thus, specific phenotypic...
17.
Alvarez M, Xu L, Childress P, Maupin K, Mohamad S, Chitteti B, et al.
Stem Cells Dev
. 2018 Apr;
27(10):671-682.
PMID: 29631496
Emerging evidence demonstrates that megakaryocytes (MK) play key roles in regulating skeletal homeostasis and hematopoiesis. To test if the loss of MK negatively impacts osteoblastogenesis and hematopoiesis, we generated conditional...
18.
Mohamad S, Xu L, Ghosh J, Childress P, Abeysekera I, Himes E, et al.
Blood Adv
. 2018 Jan;
1(26):2520-2528.
PMID: 29296903
Networking between hematopoietic stem cells (HSCs) and cells of the hematopoietic niche is critical for stem cell function and maintenance of the stem cell pool. We characterized calvariae-resident osteomacs (OMs)...
19.
Micanovic R, Khan S, Janosevic D, Lee M, Hato T, Srour E, et al.
J Am Soc Nephrol
. 2017 Nov;
29(3):841-856.
PMID: 29180395
Tamm-Horsfall protein (THP), also known as uromodulin, is a kidney-specific protein produced by cells of the thick ascending limb of the loop of Henle. Although predominantly secreted apically into the...
20.
Clinkenbeard E, Hanudel M, Stayrook K, Appaiah H, Farrow E, Cass T, et al.
Haematologica
. 2017 Aug;
102(11):e427-e430.
PMID: 28818868
No abstract available.