Edward F Srour
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Explore the profile of Edward F Srour including associated specialties, affiliations and a list of published articles.
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92
Citations
2914
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Recent Articles
1.
Childress P, Nielsen J, Bemenderfer T, Dadwal U, Chakraborty N, Harris J, et al.
J Bone Miner Res
. 2024 Nov;
40(1):125-139.
PMID: 39566068
Achieving bone union remains a significant clinical dilemma. The use of osteoinductive agents, specifically bone morphogenetic proteins (BMPs), has gained wide attention. However, multiple side effects, including increased incidence of...
2.
Mohamad S, El Koussa R, Ghosh J, Blosser R, Gunawan A, Layer J, et al.
Stem Cell Reports
. 2024 Mar;
19(4):486-500.
PMID: 38458190
Maintenance of hematopoietic stem cell (HSC) function in the niche is an orchestrated event. Osteomacs (OM) are key cellular components of the niche. Previously, we documented that osteoblasts, OM, and...
3.
Alam I, Gerard-ORiley R, Acton D, Hardman S, Murphy M, Alvarez M, et al.
FASEB J
. 2022 Aug;
36(9):e22471.
PMID: 35959867
Autosomal dominant osteopetrosis type II (ADO2) is a heritable bone disease of impaired osteoclastic bone resorption caused by missense mutations in the chloride channel 7 (CLCN7) gene. Clinical features of...
4.
LaFavers K, Hage C, Gaur V, Micanovic R, Hato T, Khan S, et al.
Am J Physiol Renal Physiol
. 2022 Jun;
323(2):F212-F226.
PMID: 35759740
Sepsis is a significant cause of mortality in hospitalized patients. Concomitant development of acute kidney injury (AKI) increases sepsis mortality through unclear mechanisms. Although electrolyte disturbances and toxic metabolite buildup...
5.
Awosanya O, Dalloul C, Blosser R, Dadwal U, Carozza M, Boschen K, et al.
Bone
. 2021 Oct;
154:116227.
PMID: 34607050
The consequences of SARS-CoV-2 infection on the musculoskeletal system represent a dangerous knowledge gap. Aging patients are at added risk for SARS-CoV-2 infection; therefore, a greater understanding of the resulting...
6.
Battina H, Alentado V, Srour E, Moliterno A, Kacena M
Exp Hematol
. 2021 Sep;
104:32-39.
PMID: 34563606
No abstract available.
7.
Alentado V, Moliterno A, Srour E, Kacena M
Cytokine
. 2021 Jul;
146:155634.
PMID: 34247039
Thrombopoietin (TPO) is most recognized for its function as the primary regulator of megakaryocyte (MK) expansion and differentiation. MKs, in turn, are best known for their role in platelet production....
8.
Ghosh J, El Koussa R, Mohamad S, Liu J, Kacena M, Srour E
Curr Opin Hematol
. 2021 May;
28(4):243-250.
PMID: 33966008
Purpose Of Review: Development and functions of hematopoietic stem cells (HSC) are regulated by multiple cellular components of the hematopoietic niche. Here we review the recent advances in studying the...
9.
Mohamad S, Gunawan A, Blosser R, Childress P, Aguilar-Perez A, Ghosh J, et al.
J Bone Miner Res
. 2021 Apr;
36(8):1580-1593.
PMID: 33900648
Osteomacs (OM) are specialized bone-resident macrophages that are a component of the hematopoietic niche and support bone formation. Also located in the niche are a second subset of macrophages, namely...
10.
Capitano M, Mohamad S, Cooper S, Guo B, Huang X, Gunawan A, et al.
J Clin Invest
. 2021 Jan;
131(1).
PMID: 33393491
Bone marrow (BM) hematopoietic stem cells (HSCs) become dysfunctional during aging (i.e., they are increased in number but have an overall reduction in long-term repopulation potential and increased myeloid differentiation)...