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Ed D Lowe

Explore the profile of Ed D Lowe including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 144
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Recent Articles
1.
Fairhead M, Shen D, Chan L, Lowe E, Donohoe T, Howarth M
Bioorg Med Chem . 2014 Aug; 22(19):5476-86. PMID: 25128469
The pathway of ligand dissociation and how binding sites respond to force are not well understood for any macromolecule. Force effects on biological receptors have been studied through simulation or...
2.
Fairhead M, Krndija D, Lowe E, Howarth M
J Mol Biol . 2013 Sep; 426(1):199-214. PMID: 24056174
Streptavidin is one of the most important hubs for molecular biology, either multimerizing biomolecules, bridging one molecule to another, or anchoring to a biotinylated surface/nanoparticle. Streptavidin has the advantage of...
3.
Davies K, Lowe E, Venien-Bryan C, Johnson L
J Mol Biol . 2008 Nov; 385(1):51-64. PMID: 18977359
Hydrogen uptake protein regulator (HupR) is a member of the nitrogen regulatory protein C (NtrC) family of response regulators. These proteins activate transcription by RNA polymerase (RNAP) in response to...
4.
Brown N, Lowe E, Petri E, Skamnaki V, Antrobus R, Johnson L
Cell Cycle . 2007 May; 6(11):1350-9. PMID: 17495531
The transitions of the cell cycle are regulated by the cyclin dependent protein kinases (CDKs). The cyclins activate their respective CDKs and confer substrate recognition properties. We report the structure...
5.
Cheng K, Noble M, Skamnaki V, Brown N, Lowe E, Kontogiannis L, et al.
J Biol Chem . 2006 May; 281(32):23167-79. PMID: 16707497
Phospho-CDK2/cyclin A, a kinase that is active in cell cycle S phase, contains an RXL substrate recognition site that is over 40 A from the catalytic site. The role of...