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Eckhard Schulz

Explore the profile of Eckhard Schulz including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 333
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Recent Articles
1.
Benndorf K, Schulz E
J Gen Physiol . 2023 Oct; 155(12). PMID: 37882789
Ligand-gated ion channels (LGICs) are regularly oligomers containing between two and five binding sites for ligands. Neither in homomeric nor heteromeric LGICs the activation process evoked by the ligand binding...
2.
Schmauder R, Eick T, Schulz E, Sammler G, Voigt E, Mayer G, et al.
Commun Biol . 2023 Oct; 6(1):1003. PMID: 37783870
Ligand-gated ion channels are formed by three to five subunits that control the opening of the pore in a cooperative fashion. We developed a microfluidic chip-based technique for studying ion...
3.
Schirmeyer J, Eick T, Schulz E, Hummert S, Sattler C, Schmauder R, et al.
PLoS Comput Biol . 2022 Aug; 18(8):e1010376. PMID: 35998156
Cyclic nucleotide-gated (CNG) ion channels of olfactory sensory neurons contain three types of homologue subunits, two CNGA2 subunits, one CNGA4 subunit and one CNGB1b subunit. Each subunit carries an intracellular...
4.
Benndorf K, Eick T, Sattler C, Schmauder R, Schulz E
J Gen Physiol . 2022 Apr; 154(6). PMID: 35486087
Ligand-gated ion channels are oligomers containing several binding sites for the ligands. However, the signal transmission from the ligand binding site to the pore has not yet been fully elucidated...
5.
Schirmeyer J, Hummert S, Eick T, Schulz E, Schwabe T, Ehrlich G, et al.
Proc Natl Acad Sci U S A . 2021 Jul; 118(30). PMID: 34301910
Cyclic nucleotide-gated (CNG) ion channels of olfactory neurons are tetrameric membrane receptors that are composed of two A2 subunits, one A4 subunit, and one B1b subunit. Each subunit carries a...
6.
Sattler C, Eick T, Hummert S, Schulz E, Schmauder R, Schweinitz A, et al.
Sci Rep . 2020 Dec; 10(1):21751. PMID: 33303878
Ionotropic purinergic (P2X) receptors are trimeric channels that are activated by the binding of ATP. They are involved in multiple physiological functions, including synaptic transmission, pain and inflammation. The mechanism...
7.
Wongsamitkul N, Nache V, Eick T, Hummert S, Schulz E, Schmauder R, et al.
Sci Rep . 2018 Jun; 8:47001. PMID: 29952374
This corrects the article DOI: 10.1038/srep20974.
8.
Nache V, Eick T, Schulz E, Schmauder R, Benndorf K
Nat Commun . 2018 Mar; 9:16207. PMID: 29600802
This corrects the article DOI: 10.1038/ncomms3866.
9.
Hummert S, Thon S, Eick T, Schmauder R, Schulz E, Benndorf K
PLoS Comput Biol . 2018 Mar; 14(3):e1006045. PMID: 29565972
Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels control electrical rhythmicity in specialized brain and heart cells. We quantitatively analysed voltage-dependent activation of homotetrameric HCN2 channels and its modulation by the second messenger...
10.
Wongsamitkul N, Nache V, Eick T, Hummert S, Schulz E, Schmauder R, et al.
Sci Rep . 2016 Feb; 6:20974. PMID: 26858151
In multimeric membrane receptors the cooperative action of the subunits prevents exact knowledge about the operation and the interaction of the individual subunits. We propose a method that permits quantification...