Eckart Bartnik
Overview
Explore the profile of Eckart Bartnik including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
452
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0
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Recent Articles
1.
Drummond S, Bartnik E, Kouvatsos N, Scott J, Dyer D, Thomson J, et al.
Osteoarthritis Cartilage
. 2023 May;
31(10):1353-1364.
PMID: 37257556
Objective: To investigate the role of endogenous TSG-6 in human osteoarthritis (OA) and assess the disease-modifying potential of a TSG-6-based biological treatment in cell, explant and animal models of OA....
2.
Sabat R, Simaite D, Gudjonsson J, Brembach T, Witte K, Krause T, et al.
J Allergy Clin Immunol
. 2022 Dec;
151(4):1015-1026.
PMID: 36481267
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by painful inflamed nodules, abscesses, and pus-draining tunnels appearing in axillary, inguinal, and perianal skin areas. HS lesions contain various...
3.
Jodeleit H, Winkelmann P, Caesar J, Sterz S, Holdt L, Beigel F, et al.
Dis Model Mech
. 2020 Dec;
14(1).
PMID: 33293281
This study's aim was to demonstrate that the combination of patient immune profiling and testing in a humanized mouse model of ulcerative colitis (UC) might lead to patient stratification for...
4.
Jodeleit H, Caesar J, Villarroel Aguilera C, Sterz S, Holdt L, Beigel F, et al.
Inflamm Bowel Dis
. 2019 Nov;
26(4):557-569.
PMID: 31782956
Background: To date, responsiveness to tumor necrosis factor alpha inhibitors in ulcerative colitis (UC) patients is not predictable. This is partially due to a lack of understanding of the underlying...
5.
Florian P, Flechsenhar K, Bartnik E, Ding-Pfennigdorff D, Herrmann M, Bryce P, et al.
Exp Dermatol
. 2019 Apr;
29(1):4-14.
PMID: 30991456
Due to the clinical development of drugs such as secukinumab, ustekinumab and dupilumab, major changes have been achieved in the treatment of patients diagnosed with psoriasis and atopic dermatitis. In...
6.
McAlindon T, Bartnik E, Ried J, Teichert L, Herrmann M, Flechsenhar K
J Biomed Res
. 2017 Aug;
31(1):25-30.
PMID: 28808182
To evaluate in an interventional trial on knee osteoarthritis (OA) the level and change of two serum biomarkers and their correlation with imaging parameters. The previously reported interventional OA study...
7.
Ried J, Flechsenhar K, Bartnik E, Crowther D, Dietrich A, Eckstein F
Arthritis Rheumatol
. 2015 Aug;
67(12):3174-83.
PMID: 26314914
Objective: To evaluate the extent to which the current designs of clinical trials in knee osteoarthritis (OA) permit detection of a therapeutic effect of disease-modifying OA drugs (DMOADs) on the...
8.
Caglic D, Globisch A, Kindermann M, Lim N, Jeske V, Juretschke H, et al.
Bioorg Med Chem
. 2010 Dec;
19(3):1055-61.
PMID: 21130662
Near-infrared fluorophore (NIRF)-labeled imaging probes are becoming increasingly important in bio-molecular imaging applications, that is, in animal models for tumor imaging or inflammation studies. In this study we showed that...
9.
Aigner T, Fundel K, Saas J, Gebhard P, Haag J, Weiss T, et al.
Arthritis Rheum
. 2006 Nov;
54(11):3533-44.
PMID: 17075858
Objective: Despite many research efforts in recent decades, the major pathogenetic mechanisms of osteoarthritis (OA), including gene alterations occurring during OA cartilage degeneration, are poorly understood, and there is no...
10.
Klatt A, Klinger G, Neumuller O, Eidenmuller B, Wagner I, Achenbach T, et al.
Biomed Pharmacother
. 2006 Feb;
60(2):55-61.
PMID: 16459052
The paper provides evidence that transforming growth factor-beta activated kinase 1 (TAK1, MEKK7), a downstream mediator of IL-1beta signal transduction, plays an important role in the regulation of catabolic events...