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E C Strauss

Explore the profile of E C Strauss including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 276
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Recent Articles
1.
Le K, Gibiansky L, van Lookeren Campagne M, Good J, Davancaze T, Loyet K, et al.
CPT Pharmacometrics Syst Pharmacol . 2015 Nov; 4(10):595-604. PMID: 26535160
Intravitreally administered lampalizumab is an investigational complement inhibitor directed against complement factor D (CFD) for the treatment of geographic atrophy (GA) secondary to age-related macular degeneration. We sought to develop...
2.
Strauss E, Orkin S
Methods Enzymol . 1999 Jun; 304:572-84. PMID: 10372382
The analysis of functional DNA regulatory sequences involved in transcriptional control is critical to establishing which proteins mediate cell-specific gene expression. The organization of erythroid LCRs is complex, consisting of...
3.
Strauss E, Larson K, Brenneise I, Foster C, Larsen G, Lee N, et al.
Invest Ophthalmol Vis Sci . 1999 Jun; 40(7):1336-42. PMID: 10359314
Purpose: To assess the anti-inflammatory modality of a soluble extracellular form of P-selectin glycoprotein ligand 1 (sPSGL-1) in a mouse model of ocular allergic response. Methods: Potential anti-inflammatory effects of...
4.
Strauss E, Orkin S
Methods . 1997 Feb; 11(2):164-70. PMID: 8993028
The identification of relevant DNA regulatory sequences involved in transcriptional control is critical to establishing which proteins mediate cell-specific gene expression. As an approach to investigating the mechanisms of gene...
5.
Strauss E, Orkin S
Proc Natl Acad Sci U S A . 1992 Jul; 89(13):5809-13. PMID: 1631062
The expression of beta-globin genes in developing erythroid cells is dependent on distant, upstream regulatory sequences, known as the locus control region (LCR), which are marked in chromatin by DNase...
6.
Strauss E, Andrews N, Higgs D, Orkin S
Mol Cell Biol . 1992 May; 12(5):2135-42. PMID: 1569944
A major regulatory element required for expression of the human alpha-globin genes is located 40 kb upstream of the embryonic zeta-globin gene. To understand how this and other locus control...
7.
Skalnik D, Strauss E, Orkin S
J Biol Chem . 1991 Sep; 266(25):16736-44. PMID: 1885602
The cytochrome b heavy chain (gp91-phox) is expressed exclusively in terminally differentiating myelomonocytic cells. The human gp91-phox gene spans approximately 30 kilobases, and is divided into 13 exons. A ubiquitous...
8.
Siu G, Strauss E, Lai E, HOOD L
J Exp Med . 1986 Nov; 164(5):1600-14. PMID: 3772297
We have isolated and sequenced five germline V beta gene segments that are homologous to the V region of the YT35 cDNA encoding the beta chain of the T cell...
9.
Strauss E, Kobori J, Siu G, HOOD L
Anal Biochem . 1986 Apr; 154(1):353-60. PMID: 3010776
A simple and rapid strategy for DNA sequence analysis based on the Sanger chain-termination method is described. This procedure utilizes full-sized inserts of 1 to 4 kb of DNA cloned...