Duncan G G McMillan
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Explore the profile of Duncan G G McMillan including associated specialties, affiliations and a list of published articles.
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37
Citations
556
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Recent Articles
1.
Juergens H, Mielgo-Gomez A, Godoy-Hernandez A, Ter Horst J, Nijenhuis J, McMillan D, et al.
Front Microbiol
. 2024 Dec;
15:1473869.
PMID: 39726963
Mitochondria from harbor a branched electron-transport chain containing a proton-pumping Complex I NADH dehydrogenase and three Type II NADH dehydrogenases (NDH-2). To investigate the physiological role, localization and substrate specificity...
2.
Quantitative proteomics reveals oxygen-induced adaptations in TA2.A1 microaerobic chemostat cultures
de Jong S, Wissink M, Yildirim K, Pabst M, van Loosdrecht M, McMillan D
Front Microbiol
. 2024 Nov;
15:1468929.
PMID: 39529675
The thermoalkaliphile possesses a highly branched respiratory chain. These primarily facilitate growth at a wide range of dissolved oxygen levels. The aim of this study was to investigate the regulation...
3.
de Jong S, Sorokin D, van Loosdrecht M, Pabst M, McMillan D
Front Microbiol
. 2023 Aug;
14:1228266.
PMID: 37577439
Proteomics has greatly advanced the understanding of the cellular biochemistry of microorganisms. The thermoalkaliphile TA2.A1 is an organism of interest for studies into how alkaliphiles adapt to their extreme lifestyles,...
4.
Godoy-Hernandez A, Asseri A, Purugganan A, Jiko C, de Ram C, Lill H, et al.
ACS Cent Sci
. 2023 Mar;
9(3):494-507.
PMID: 36968527
Functional reintegration into lipid environments represents a major challenge for investigation of integral membrane proteins (IMPs). Here, we report a new approach, termed LMNG Auto-insertion Reintegration (LAiR), for reintegration of...
5.
Krah A, Vogelaar T, de Jong S, Claridge J, Bond P, McMillan D
Front Mol Biosci
. 2023 Mar;
10:1059673.
PMID: 36923639
It is a conjecture that the ε subunit regulates ATP hydrolytic function of the FF ATP synthase in bacteria. This has been proposed by the ε subunit taking an extended...
6.
Marsden S, Wijma H, Mohr M, Justo I, Hagedoorn P, Laustsen J, et al.
Angew Chem Int Ed Engl
. 2022 Oct;
61(49):e202213338.
PMID: 36214476
Regulation of enzyme activity is vital for living organisms. In metalloenzymes, far-reaching rearrangements of the protein scaffold are generally required to tune the metal cofactor's properties by allosteric regulation. Here...
7.
Kleikamp H, Lin Y, McMillan D, Geelhoed J, Naus-Wiezer S, van Baarlen P, et al.
Chem Sci
. 2021 Jun;
11(11):3074-3080.
PMID: 34122812
Nonulosonic acids, commonly referred to as sialic acids, are a highly important group of nine-carbon sugars common to all domains of life. They all share biosynthetic and structural features, but...
8.
Godoy-Hernandez A, McMillan D
Membranes (Basel)
. 2021 Jun;
11(5).
PMID: 34067848
Lipids play a pivotal role in cellular respiration, providing the natural environment in which an oxidoreductase interacts with the quinone pool. To date, it is generally accepted that negatively charged...
9.
Boes D, Godoy-Hernandez A, McMillan D
Membranes (Basel)
. 2021 Jun;
11(5).
PMID: 34066904
Membrane proteins can be classified into two main categories-integral and peripheral membrane proteins-depending on the nature of their membrane interaction. Peripheral membrane proteins are highly unique amphipathic proteins that interact...
10.
Asseri A, Godoy-Hernandez A, Goojani H, Lill H, Sakamoto J, McMillan D, et al.
Sci Rep
. 2021 Apr;
11(1):8006.
PMID: 33850195
Cardiolipin (CL) is a lipid that is found in the membranes of bacteria and the inner membranes of mitochondria. CL can increase the activity of integral membrane proteins, in particular...