Douglas H Turner
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Explore the profile of Douglas H Turner including associated specialties, affiliations and a list of published articles.
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105
Citations
3438
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Recent Articles
21.
Lenartowicz E, Kesy J, Ruszkowska A, Soszynska-Jozwiak M, Michalak P, Moss W, et al.
PLoS One
. 2016 Feb;
11(2):e0148281.
PMID: 26848969
Influenza A is a negative sense RNA virus that kills hundreds of thousands of humans each year. Base pairing in RNA is very favorable, but possibilities for RNA secondary structure...
22.
Reblova K, Strelcova Z, Kulhanek P, Besseova I, Mathews D, Van Nostrand K, et al.
J Chem Theory Comput
. 2015 Nov;
6(3):910-29.
PMID: 26613316
Functional RNA molecules such as ribosomal RNAs (rRNAs) frequently contain highly conserved internal loops with a 5'-UAA/5'-GAN (UAA/GAN) consensus sequence. The UAA/GAN internal loops adopt a distinctive structure inconsistent with...
23.
Chen J, Bellaousov S, Tubbs J, Kennedy S, Lopez M, Mathews D, et al.
Biochemistry
. 2015 Oct;
54(45):6769-82.
PMID: 26451676
Knowledge of RNA structure is necessary to determine structure-function relationships and to facilitate design of potential therapeutics. RNA secondary structure prediction can be improved by applying constraints from nuclear magnetic...
24.
Condon D, Kennedy S, Mort B, Kierzek R, Yildirim I, Turner D
J Chem Theory Comput
. 2015 Jun;
11(6):2729-2742.
PMID: 26082675
Molecular dynamics (MD) simulations for RNA tetramers r(AAAA), r(CAAU), r(GACC), and r(UUUU) are benchmarked against H-H NOESY distances and scalar couplings to test effects of RNA torsion parametrizations. Four different...
25.
Priore S, Kauffmann A, Baman J, Turner D
Biochemistry
. 2015 May;
54(22):3413-5.
PMID: 25996464
Influenza A is a negative-sense RNA virus with an eight-segment genome. Some segments encode more than one polypeptide product, but how the virus accesses alternate internal open reading frames (ORFs)...
26.
Chen J, Kennedy S, Turner D
Biochemistry
. 2015 Apr;
54(21):3269-85.
PMID: 25909229
Influenza A is an RNA virus with a genome of eight negative sense segments. Segment 7 mRNA contains a 3' splice site for alternative splicing to encode the essential M2...
27.
Kierzek R, Turner D, Kierzek E
Nucleic Acids Res
. 2014 Dec;
43(1):1-12.
PMID: 25505162
Oligonucleotide microarrays are widely used in various biological studies. In this review, application of oligonucleotide microarrays for identifying binding sites and probing structure of RNAs is described. Deep sequencing allows...
28.
Jiang T, Kennedy S, Moss W, Kierzek E, Turner D
Biochemistry
. 2014 Jul;
53(32):5236-48.
PMID: 25026548
Influenza A virus utilizes RNA throughout infection. Little is known, however, about the roles of RNA structures. A previous bioinformatics survey predicted multiple regions of influenza A virus that are...
29.
Andronescu M, Condon A, Turner D, Mathews D
Methods Mol Biol
. 2014 Mar;
1097:45-70.
PMID: 24639154
The stability of RNA secondary structure can be predicted using a set of nearest neighbor parameters. These parameters are widely used by algorithms that predict secondary structure. This contribution introduces...
30.
Sripakdeevong P, Cevec M, Chang A, Erat M, Ziegeler M, Zhao Q, et al.
Nat Methods
. 2014 Mar;
11(4):413-6.
PMID: 24584194
Structured noncoding RNAs underlie fundamental cellular processes, but determining their three-dimensional structures remains challenging. We demonstrate that integrating ¹H NMR chemical shift data with Rosetta de novo modeling can be...