Ryszard Kierzek
Overview
Explore the profile of Ryszard Kierzek including associated specialties, affiliations and a list of published articles.
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107
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1821
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Recent Articles
1.
Angelo M, Bhargava Y, Kierzek E, Kierzek R, Hayes R, Zhang W, et al.
bioRxiv
. 2024 Dec;
PMID: 39713306
RNA-binding proteins shape biology through their widespread functions in RNA biochemistry. Their function requires the recognition of specific RNA motifs for targeted binding. These RNA binding elements can be composed...
2.
Yildirim I, Andralojc W, Taghavi A, Baranowski D, Gdaniec Z, Kierzek R, et al.
Nucleic Acids Res
. 2024 Dec;
53(1.
PMID: 39711475
Although glycosidic bonds in purines typically involve the N9 position, the chemical synthesis of adenosine produces N7-ribofuranosyladenine (7A) as a kinetically favorable ribosylation product. Similarly, in the synthesis of LNA-adenosine...
3.
Jarmolowicz A, Dutta N, Andralojc W, Sarzynska J, Framski G, Baranowski D, et al.
RNA
. 2024 Oct;
31(1):86-99.
PMID: 39467648
During the chemical synthesis of the purine riboside, N7-regioisomer is kinetically formed, whereas N9-regioisomer is a thermodynamically formed product. We have studied the effect of substituting N9-regioisomer of guanosine with...
4.
Nowak R, Gazecka M, Hoffmann M, Kierzek R, Pohlmann S, Zmora P
Virology
. 2024 Sep;
600:110218.
PMID: 39276670
Emerging viruses, such as novel influenza A viruses (IAV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pose a constant threat to animal and human health. Identification of host cell...
5.
Baliga-Gil A, Soszynska-Jozwiak M, Ruszkowska A, Szczesniak I, Kierzek R, Ciechanowska M, et al.
Antiviral Res
. 2024 Jun;
228:105946.
PMID: 38925369
SARS-CoV-2 is a betacoronavirus that causes COVID-19, a global pandemic that has resulted in many infections, deaths, and socio-economic challenges. The virus has a large positive-sense, single-stranded RNA genome of...
6.
Koralewska N, Corradi E, Milewski M, Masante L, Szczepanska A, Kierzek R, et al.
Nucleic Acids Res
. 2024 Apr;
52(10):5804-5824.
PMID: 38676942
MicroRNAs (miRNAs) that share identical or near-identical sequences constitute miRNA families and are predicted to act redundantly. Yet recent evidence suggests that members of the same miRNA family with high...
7.
Mirska B, Wozniak T, Lorent D, Ruszkowska A, Peterson J, Moss W, et al.
Cell Mol Life Sci
. 2023 May;
80(5):136.
PMID: 37131079
Influenza A virus (IAV) is a respiratory virus that causes epidemics and pandemics. Knowledge of IAV RNA secondary structure in vivo is crucial for a better understanding of virus biology....
8.
Czapik T, Piasecka J, Kierzek R, Kierzek E
Mol Ther Nucleic Acids
. 2022 Jul;
29:64-74.
PMID: 35784013
The naturally occurring structure and biological functions of RNA are correlated, which includes hammerhead ribozymes. We proposed new variants of hammerhead ribozymes targeting conserved structural motifs of segment 5 of...
9.
Magner D, Nowak R, Lenartowicz Onyekaa E, Pasternak A, Kierzek R
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628656
Among types of trinucleotide repeats, there is some disproportion in the frequency of their occurrence in the human exome. This research presents new data describing the folding and thermodynamic stability...
10.
Szabat M, Prochota M, Kierzek R, Kierzek E, Mathews D
J Mol Biol
. 2022 May;
434(18):167632.
PMID: 35588868
RNA folding free energy change parameters are widely used to predict RNA secondary structure and to design RNA sequences. These parameters include terms for the folding free energies of helices...