Douangsone D Vadysirisack
Overview
Explore the profile of Douangsone D Vadysirisack including associated specialties, affiliations and a list of published articles.
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18
Citations
953
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Recent Articles
1.
Tang G, Tang Y, Dhamnaskar K, Hoarty M, Vyasamneni R, Vadysirisack D, et al.
Front Immunol
. 2023 Oct;
14:1282155.
PMID: 37818356
[This corrects the article DOI: 10.3389/fimmu.2023.1213920.].
2.
Tang G, Tang Y, Dhamnaskar K, Hoarty M, Vyasamneni R, Vadysirisack D, et al.
Front Immunol
. 2023 Aug;
14:1213920.
PMID: 37622108
Introduction: The complement system is a key component of the innate immune system, and its aberrant activation underlies the pathophysiology of various diseases. Zilucoplan is a macrocyclic peptide that binds...
3.
Kulasekararaj A, Lehtinen A, Forsyth C, Gandhi S, Griffin M, Korper S, et al.
Haematologica
. 2023 Aug;
109(3):929-935.
PMID: 37534517
No abstract available.
4.
Obaid A, Zografou C, Vadysirisack D, Munro-Sheldon B, Fichtner M, Roy B, et al.
Neurol Neuroimmunol Neuroinflamm
. 2022 Apr;
9(4).
PMID: 35473886
Background And Objectives: Autoantibodies targeting the acetylcholine receptor (AChR), found in patients with myasthenia gravis (MG), mediate pathology through 3 mechanisms: complement-directed tissue damage, blocking of the acetylcholine binding site,...
5.
Fichtner M, Hoarty M, Vadysirisack D, Munro-Sheldon B, Nowak R, OConnor K
PLoS One
. 2022 Mar;
17(3):e0264489.
PMID: 35290370
Acetylcholine receptor (AChR) autoantibodies, found in patients with autoimmune myasthenia gravis (MG), can directly contribute to disease pathology through activation of the classical complement pathway. Activation of the complement pathway...
6.
Muldur S, Vadysirisack D, Ragunathan S, Tang Y, Ricardo A, Sayegh C, et al.
Front Immunol
. 2021 Dec;
12:777932.
PMID: 34899737
Complement activation is key to anti-microbial defenses by directly acting on microbes and indirectly by triggering cellular immune responses. Complement activation may also contribute to the pathogenesis of numerous inflammatory...
7.
Qiao S, Dennis M, Song X, Vadysirisack D, Salunke D, Nash Z, et al.
Nat Commun
. 2015 Apr;
6:7014.
PMID: 25916556
Macroautophagy (autophagy) is a critical cellular stress response; however, the signal transduction pathways controlling autophagy induction in response to stress are poorly understood. Here we reveal a new mechanism of...
8.
Vadysirisack D, Ellisen L
Methods Mol Biol
. 2011 Nov;
821:45-58.
PMID: 22125059
The adaptive response to hypoxia, low oxygen tension, involves inhibition of energy-intensive cellular processes including protein translation. This effect is mediated in part through a decrease in the kinase activity...
9.
Feedback control of p53 translation by REDD1 and mTORC1 limits the p53-dependent DNA damage response
Vadysirisack D, Baenke F, Ory B, Lei K, Ellisen L
Mol Cell Biol
. 2011 Sep;
31(21):4356-65.
PMID: 21896779
Exquisite control of the level and activity of p53 are required in order to preserve cellular homeostasis following DNA damage. How this regulation is integrated with other key metabolic pathways...
10.
Ory B, Ramsey M, Wilson C, Vadysirisack D, Forster N, Rocco J, et al.
J Clin Invest
. 2011 Feb;
121(2):809-20.
PMID: 21293058
The p53 tumor suppressor, a central mediator of chemosensitivity in normal cells, is functionally inactivated in many human cancers. Therefore, a central challenge in human cancer therapy is the identification...