Douangsone D Vadysirisack
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Explore the profile of Douangsone D Vadysirisack including associated specialties, affiliations and a list of published articles.
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18
Citations
953
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Recent Articles
11.
Horak P, Crawford A, Vadysirisack D, Nash Z, DeYoung M, Sgroi D, et al.
Proc Natl Acad Sci U S A
. 2010 Feb;
107(10):4675-80.
PMID: 20176937
The HIF family of hypoxia-inducible transcription factors are key mediators of the physiologic response to hypoxia, whose dysregulation promotes tumorigenesis. One important HIF-1 effector is the REDD1 protein, which is...
12.
Zhong L, DUrso A, Toiber D, Sebastian C, Henry R, Vadysirisack D, et al.
Cell
. 2010 Feb;
140(2):280-93.
PMID: 20141841
SIRT6 is a member of a highly conserved family of NAD(+)-dependent deacetylases with various roles in metabolism, stress resistance, and life span. SIRT6-deficient mice develop normally but succumb to a...
13.
Vadysirisack D, Chen E, Zhang Z, Tsai M, Chang G, Jhiang S
J Biol Chem
. 2007 Oct;
282(51):36820-8.
PMID: 17913707
The Na+/I- symporter (NIS)-mediated iodide uptake activity is the basis for targeted radioiodide ablation of thyroid cancers. Although it has been shown that NIS protein is phosphorylated, neither the in...
14.
Vadysirisack D, Venkateswaran A, Zhang Z, Jhiang S
Endocr Relat Cancer
. 2007 Jul;
14(2):421-32.
PMID: 17639055
The Na(+)/I(-) symporter (NIS)-mediated iodide uptake is the basis for targeted radioiodine ablation of thyroid cancers. However, NIS-mediated radioiodide uptake (RAIU) activity is often reduced in thyroid cancers. As mitogen...
15.
Vadysirisack D, Shen D, Jhiang S
J Nucl Med
. 2006 Jan;
47(1):182-90.
PMID: 16391203
Unlabelled: The Na(+)/I(-) symporter (NIS) has been proposed as an imaging reporter gene to ascertain the expression of therapeutic genes in targeted tissues. In this study, we investigated whether posttranslational...
16.
Morgenstern K, Vadysirisack D, Zhang Z, Cahill K, Foster J, Burns J, et al.
Ophthalmic Plast Reconstr Surg
. 2005 Oct;
21(5):337-44.
PMID: 16234694
Purpose: Nasolacrimal outflow obstruction has been associated with high-dose (>150 mCi) radioactive iodine (I(131)) treatment. Commonly used for thyroid cancer treatment, I(131) is effectively transported in the targeted tissue by...
17.
Marsee D, Vadysirisack D, Morrison C, Prasad M, Eng C, Duh Q, et al.
Thyroid
. 2005 Sep;
15(9):977-87.
PMID: 16187905
Adenoviral gene therapy represents a novel approach for the treatment of aggressive thyroid carcinomas. Both coxsackie-adenovirus receptor (CAR) and integrins have been shown to be the major determinants for adenoviral...
18.
Marsee D, Shen D, MacDonald L, Vadysirisack D, Lin X, Hinkle G, et al.
Cancer Gene Ther
. 2004 Jan;
11(2):121-7.
PMID: 14730332
The Na+/I- symporter (NIS) is a membrane glycoprotein that facilitates the uptake of iodine into thyroid follicular cells. Recently, we and others have demonstrated the feasibility of imaging subcutaneous xenografts...