Dong-Ki Lee
Overview
Explore the profile of Dong-Ki Lee including associated specialties, affiliations and a list of published articles.
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86
Citations
1930
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Recent Articles
1.
Ban J, Seo B, Yu Y, Kim M, Choe J, Park J, et al.
Drug Metab Dispos
. 2024 Aug;
52(11):1262-1270.
PMID: 39168524
In this study, the nonclinical pharmacokinetics of OLX702A-075-16, an RNA interference therapeutic currently in development, were investigated. OLX702A-075-16 is a novel -acetylgalactosamine conjugated asymmetric small-interfering RNA (GalNAc-asiRNA) used for the...
2.
Lee S, Jang S, Chung M, Cho J, Do M, Lee H, et al.
J Clin Med
. 2024 Apr;
13(5).
PMID: 38592022
: This study evaluated the effectiveness of short fully covered self-expanding metal stents (FCSEMS) with an anti-migration design in treating benign biliary strictures (BBS) not related to living donor liver...
3.
Kim S, Kang Y, Kim J, Dua P, Lee D
Nucleic Acid Ther
. 2023 Oct;
33(5):329-337.
PMID: 37797162
Post-transcriptional regulation of transcript abundances by RNA interference (i) is a widely conserved regulatory mechanism to control cellular processes. We previously introduced an alternative siRNA structure called asymmetric siRNA (asiRNA),...
4.
Efficacy of Asymmetric siRNA Targeting Androgen Receptors for the Treatment of Androgenetic Alopecia
Moon I, Yoon H, Kim D, Choi M, Han S, Park J, et al.
Mol Pharm
. 2022 Nov;
20(1):128-135.
PMID: 36352823
Asymmetric small interfering RNAs (asiRNAs) that mediate RNA interference have been investigated for therapeutic use in various tissues, including skin tissue. Androgenetic alopecia (AGA) is caused by a combination of...
5.
Ren S, Cho S, Lin R, Gedi V, Park S, Ahn C, et al.
Biosensors (Basel)
. 2022 Oct;
12(10).
PMID: 36291000
Spiegelmers are enantiomers of natural D-oligonucleotides that bind to targets with distinct structures such as aptamers. The high susceptibility of natural D-form aptamers to nucleases greatly hinders their application in...
6.
Jang S, Cho J, Kim S, Hong I, Park J, Lee H, et al.
Cancers (Basel)
. 2022 Feb;
14(3).
PMID: 35159120
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer for which no early diagnostic method is available. The immune surveillance hypothesis suggests that the immune system plays crucial roles in tumor...
7.
Do M, Jang S, Kang H, Kim E, Lee K, Park G, et al.
Cancers (Basel)
. 2021 Sep;
13(18).
PMID: 34572940
Neuroendocrine neoplasms (NENs) of the gallbladder (GB) are extremely rare. We aimed to compare the clinical features, disease progression, management, and prognosis of patients with GB-NENs with those of patients...
8.
Sajeesh S, Choe J, Lee T, Lee D
J Mater Chem B
. 2020 Apr;
3(2):207-216.
PMID: 32261941
Combination therapy involving the synergism between different therapeutic approaches seems to be a promising strategy in anticancer treatment. Immunostimulatory long interfering RNA (liRNA) structures capable of executing specific RNA interference...
9.
Choe J, Son D, Kim Y, Lee J, Shin H, Kim W, et al.
Mol Pharm
. 2020 Jan;
17(3):777-786.
PMID: 31976668
The efficient delivery of small interfering RNAs (siRNAs) to the target cells is critical for the pharmaceutical success of RNA interference (RNAi) drugs. One of the possible strategies to improve...
10.
Lee S, Kim B, Shin H, Go A, Lee M, Lee D, et al.
Micromachines (Basel)
. 2019 Nov;
10(11).
PMID: 31718045
Here, we report a simple and effective method for capturing and displacement of gram-negative bacteria using aptamer-modified microbeads and acoustophoresis. As acoustophoresis allows for simultaneous washing and size-dependent separation in...