Donald Gullberg
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Explore the profile of Donald Gullberg including associated specialties, affiliations and a list of published articles.
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73
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2487
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Recent Articles
1.
Chang J, Pickard A, Herrera J, OKeefe S, Garva R, Hartshorn M, et al.
Elife
. 2025 Jan;
13.
PMID: 39812558
Collagen-I fibrillogenesis is crucial to health and development, where dysregulation is a hallmark of fibroproliferative diseases. Here, we show that collagen-I fibril assembly required a functional endocytic system that recycles...
2.
Musiime M, Erusappan P, Cukierman E, Chang J, Molven A, Hansen U, et al.
Matrix Biol
. 2024 Oct;
134:144-161.
PMID: 39406317
Solid epithelial cancers with significant desmoplasia are characterized by an excessive deposition of collagen-based matrix, which often supports tumor progression. However, the mechanism of how collagen receptors mediate collagen fibrillogenesis...
3.
Stewart D, Brisson B, Yen W, Liu Y, Wang C, Ruthel G, et al.
J Invest Dermatol
. 2024 Sep;
PMID: 39236902
Postnatal cutaneous wound healing is characterized by development of a collagen-rich scar lacking the architecture and functional integrity of unwounded tissue. Directing cell behaviors to efficiently heal wounds while minimizing...
4.
Zeltz C, Kusche-Gullberg M, Heljasvaara R, Gullberg D
Curr Opin Cell Biol
. 2023 Nov;
85:102273.
PMID: 37918273
Recent data indicate that integrin and non-integrin collagen receptors cooperate in the fibrosis-specific microenvironment (i.e., the fibrotic niche). In certain tumor types, DDR1 can regulate the interaction with collagen III...
5.
Bieber K, Bezdek S, Gupta Y, Vorobyev A, Sezin T, Gross N, et al.
J Pathol
. 2023 Aug;
261(2):184-197.
PMID: 37565309
Psoriasis is a chronic inflammatory skin condition. Repeated epicutaneous application of Aldara® (imiquimod) cream results in psoriasiform dermatitis in mice. The Aldara®-induced psoriasiform dermatitis (AIPD) mouse model has been used...
6.
Sawant M, Wang F, Koester J, Niehoff A, Nava M, Lundgren-Akerlund E, et al.
Ann Rheum Dis
. 2023 Jul;
82(11):1474-1486.
PMID: 37479494
Objectives: Activation of fibroblasts is a hallmark of fibrotic processes. Besides cytokines and growth factors, fibroblasts are regulated by the extracellular matrix environment through receptors such as integrins, which transduce...
7.
Farndale R, Sonnenberg A, DiPersio C, Eble J, Heino J, Gullberg D
Matrix Biol
. 2022 Dec;
115:128-132.
PMID: 36574820
No abstract available.
8.
Martinez-Nieto G, Teppo H, Petrelius N, Izzi V, Devarajan R, Petaisto T, et al.
Front Oncol
. 2022 Aug;
12:981009.
PMID: 36003785
Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing. The expression of the α11 is upregulated...
9.
Romaine A, Melleby A, Alam J, Lobert V, Lu N, Lockwood F, et al.
Am J Physiol Heart Circ Physiol
. 2022 May;
322(6):H1057-H1071.
PMID: 35522553
Pathological myocardial hypertrophy in response to an increase in left ventricular (LV) afterload may ultimately lead to heart failure. Cell surface receptors bridge the interface between the cell and the...
10.
Zeltz C, Navab R, Heljasvaara R, Kusche-Gullberg M, Lu N, Tsao M, et al.
J Cell Commun Signal
. 2022 Apr;
16(4):649-660.
PMID: 35378690
There is currently an increased interest in understanding the role of the tumor microenvironment (TME) in tumor growth and progression. In this context the role of integrins in cancer-associated fibroblasts...