Dominik Lindenhofer
Overview
Explore the profile of Dominik Lindenhofer including associated specialties, affiliations and a list of published articles.
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7
Citations
443
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Recent Articles
1.
Lindenhofer D, Haendeler S, Esk C, Littleboy J, Avalos C, Naas J, et al.
Nat Cell Biol
. 2024 May;
26(5):710-718.
PMID: 38714853
During brain development, neural progenitors expand through symmetric divisions before giving rise to differentiating cell types via asymmetric divisions. Transition between those modes varies among individual neural stem cells, resulting...
2.
Pflug F, Haendeler S, Esk C, Lindenhofer D, Knoblich J, von Haeseler A
PLoS Comput Biol
. 2024 Apr;
20(4):e1012054.
PMID: 38648250
Neural organoids model the development of the human brain and are an indispensable tool for studying neurodevelopment. Whole-organoid lineage tracing has revealed the number of progenies arising from each initial...
3.
Kornienko J, Rodriguez-Martinez M, Fenzl K, Hinze F, Schraivogel D, Grosch M, et al.
Nat Commun
. 2023 Jul;
14(1):4312.
PMID: 37463913
Severe forms of dilated cardiomyopathy (DCM) are associated with point mutations in the alternative splicing regulator RBM20 that are frequently located in the arginine/serine-rich domain (RS-domain). Such mutations can cause...
4.
Esk C, Lindenhofer D, Haendeler S, Wester R, Pflug F, Schroeder B, et al.
Science
. 2020 Oct;
370(6519):935-941.
PMID: 33122427
Loss-of-function (LOF) screens provide a powerful approach to identify regulators in biological processes. Pioneered in laboratory animals, LOF screens of human genes are currently restricted to two-dimensional cell cultures, which...
5.
Verheyen T, Fang T, Lindenhofer D, Wang Y, Akopyan K, Lindqvist A, et al.
Nucleic Acids Res
. 2020 May;
48(10):5777-5787.
PMID: 32352518
Ligand binding induces extensive spatial reorganization and clustering of the EphA2 receptor at the cell membrane. It has previously been shown that the nanoscale spatial distribution of ligands modulates EphA2...
6.
Wimmer R, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, et al.
Nature
. 2019 Jan;
565(7740):505-510.
PMID: 30651639
The increasing prevalence of diabetes has resulted in a global epidemic. Diabetes is a major cause of blindness, kidney failure, heart attacks, stroke and amputation of lower limbs. These are...
7.
Brillante N, Gossringer M, Lindenhofer D, Toth U, Rossmanith W, Hartmann R
Nucleic Acids Res
. 2016 Feb;
44(5):2323-36.
PMID: 26896801
RNase P is the enzyme that removes 5' extensions from tRNA precursors. With its diversity of enzyme forms-either protein- or RNA-based, ranging from single polypeptides to multi-subunit ribonucleoproteins-the RNase P...