Do Soo Jang
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Explore the profile of Do Soo Jang including associated specialties, affiliations and a list of published articles.
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Citations
65
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Recent Articles
1.
Cha H, Jang D, Jin K, Choi K
Amino Acids
. 2017 Feb;
49(4):715-723.
PMID: 28144743
We analyzed the structure of horseradish peroxidase (HRP) under denaturing conditions of 9 M urea or 6 M guanidine hydrochloride (GdnHCl). Far-UV circular dichroism (CD) spectra indicated the existence of...
2.
Cha H, Jang D, Jeong J, Hong B, Yun Y, Shin E, et al.
Biochim Biophys Acta
. 2016 Jul;
1864(10):1322-7.
PMID: 27375051
Ketosteroid isomerase (3-oxosteroid Δ(5)-Δ(4)-isomerase, KSI) from Pseudomonas putida catalyzes allylic rearrangement of the 5,6-double bond of Δ(5)-3-ketosteroid to 4,5-position by stereospecific intramolecular transfer of a proton. The active site of...
3.
Contribution of a low-barrier hydrogen bond to catalysis is not significant in ketosteroid isomerase
Jang D, Choi G, Cha H, Shin S, Hong B, Lee H, et al.
Mol Cells
. 2015 May;
38(5):409-15.
PMID: 25947291
Low-barrier hydrogen bonds (LBHBs) have been proposed to have important influences on the enormous reaction rate increases achieved by many enzymes. Δ(5)-3-ketosteroid isomerase (KSI) catalyzes the allylic isomerization of Δ(5)-3-ketosteroid...
4.
Cha H, Jang D, Kim Y, Hong B, Woo J, Kim K, et al.
Mol Cells
. 2013 Jun;
36(1):39-46.
PMID: 23740430
Proteins have evolved to compensate for detrimental mutations. However, compensatory mechanisms for protein defects are not well understood. Using ketosteroid isomerase (KSI), we investigated how second-site mutations could recover defective...
5.
Kim E, Jang D, Yang S, Lee M, Jin K, Cha H, et al.
Nanoscale
. 2013 Apr;
5(10):4262-9.
PMID: 23546513
Nanotechnology has been applied to the development of more effective and compatible drug delivery systems for therapeutic proteins. Human growth hormone (hGH) was fused with a hybrid Fc fragment containing...
6.
Im S, Yang S, Yang S, Choi D, Choi S, Kim H, et al.
PLoS One
. 2011 Sep;
6(9):e24574.
PMID: 21957455
Human IgG1 Fc has been widely used as a bioconjugate, but exhibits shortcomings, such as antibody- and complement-mediated cytotoxicity as well as decreased bioactivity, when applied to agonistic proteins. Here,...
7.
Hong B, Oh S, Ju J, Hong B, Jang D, Yun Y, et al.
Mol Cells
. 2010 Dec;
30(6):575-9.
PMID: 21120630
No abstract available.
8.
Lee H, Jang D, Cha H, Moon H, Hong B, Choi K, et al.
J Biochem
. 2008 Apr;
144(2):215-21.
PMID: 18442985
Multidimensional NMR was employed to investigate the structural changes in the urea-induced equilibrium unfolding of the dimeric ketosteroid isomerase (KSI) from Pseudomonas putida biotype B. Sequence specific backbone assignments for...
9.
Lee H, Yoon Y, Jang D, Kim C, Cha H, Hong B, et al.
J Biochem
. 2008 Apr;
144(2):159-66.
PMID: 18424811
The backbone dynamics of Y14F mutant of Delta(5)-3-ketosteroid isomerase (KSI) from Comamonas testosteroni has been studied in free enzyme and its complex with a steroid analogue, 19-nortestosterone hemisuccinate (19-NTHS), by...
10.
Lee H, Moon H, Jang D, Cha H, Hong B, Choi K, et al.
J Biomol NMR
. 2007 Nov;
40(1):65-70.
PMID: 18004666
We used xenon-perturbed 1H-15N multidimensional NMR to investigate the structural changes in the urea-induced equilibrium unfolding of the dimeric ketosteroid isomerase (KSI) from Pseudomonas putida biotype B. Three limited regions...