Kwan Yong Choi
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Explore the profile of Kwan Yong Choi including associated specialties, affiliations and a list of published articles.
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61
Citations
816
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Recent Articles
1.
Shin J, Park C, Yoon G, Hong S, Choi K
Oncogenesis
. 2018 Aug;
7(8):58.
PMID: 30093610
Nicotinamide N-methyl transferase (NNMT) transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide (NAM), producing 1-methylnicotinamide (1MNA). NNMT has been implicated in several cancer types and recently in metabolism, but...
2.
Lee N, Kim D, Han S, Ryu H, Park S, Kim K, et al.
Mol Cells
. 2017 Sep;
40(9):621-631.
PMID: 28927264
Vaccinia-related kinase 1 (VRK1) and VRK3 are members of the VRK family of serine/threonine kinases and are principally localized in the nucleus. Despite the crucial roles of VRK1/VRK3 in physiology...
3.
Jung H, Lee D, Ryu H, Choi B, Go Y, Lee N, et al.
Sci Rep
. 2017 Jul;
7(1):6237.
PMID: 28740165
Robust mitochondrial respiration provides energy to support physical performance and physiological well-being, whereas mitochondrial malfunction is associated with various pathologies and reduced longevity. In the current study, we tested whether...
4.
Cha H, Jang D, Jin K, Choi K
Amino Acids
. 2017 Feb;
49(4):715-723.
PMID: 28144743
We analyzed the structure of horseradish peroxidase (HRP) under denaturing conditions of 9 M urea or 6 M guanidine hydrochloride (GdnHCl). Far-UV circular dichroism (CD) spectra indicated the existence of...
5.
Kim E, Kwon J, Shin J, You S, Hong S, Choi K
Appl Biochem Biotechnol
. 2017 Jan;
182(4):1276-1289.
PMID: 28083769
The conventional gene expression profiling approaches have been replaced with DNA microarrays with exhibiting a powerful high-throughput capacity. Most solid surfaces of DNA microarrays contain such a high area density...
6.
Lee N, Park S, Haddad G, Kim D, Park S, Park S, et al.
Sci Rep
. 2016 Dec;
6:39049.
PMID: 27976729
RE-1 silencing transcription factor (REST) is a transcriptional repressor that regulates gene expression by binding to repressor element 1. However, despite its critical function in physiology, little is known about...
7.
Lee N, Ryu H, Kwon J, Kim D, Kim S, Wang H, et al.
PLoS One
. 2016 Nov;
11(11):e0165835.
PMID: 27824900
The role of Sirtuin 6 (SIRT6) as a tumor suppressor or oncogene in liver cancer remains controversial. Thus, we identified the specific role of SIRT6 in the progression of hepatocellular...
8.
Cha H, Jang D, Jeong J, Hong B, Yun Y, Shin E, et al.
Biochim Biophys Acta
. 2016 Jul;
1864(10):1322-7.
PMID: 27375051
Ketosteroid isomerase (3-oxosteroid Δ(5)-Δ(4)-isomerase, KSI) from Pseudomonas putida catalyzes allylic rearrangement of the 5,6-double bond of Δ(5)-3-ketosteroid to 4,5-position by stereospecific intramolecular transfer of a proton. The active site of...
9.
Lee N, Kwon J, Kim Y, Kim S, Park S, Xu W, et al.
Oncotarget
. 2015 Sep;
6(30):30130-48.
PMID: 26375549
We identified the specific role of vaccinia-related kinase 1 (VRK1) in the progression of hepatocellular carcinoma (HCC) and evaluated its therapeutic and prognostic potential. VRK1 levels were significantly higher in...
10.
Kwon J, Ahn K, Moon Y, Park J, Wang H, Choi K, et al.
J Korean Med Sci
. 2015 Sep;
30(9):1253-9.
PMID: 26339164
Despite a low risk of liver failure and preserved liver function, non-cirrhotic hepatocellular carcinoma (HCC) has a poor prognosis. In the current study, we evaluated an active regulator of SIRT1...